STRINGSTRING
nirD protein (Salmonella enterica CT18) - STRING interaction network
"nirD" - Nitrite reductase in Salmonella enterica CT18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirDNitrite reductase (NADH) small subunit; Required for activity of the reductase (108 aa)    
Predicted Functional Partners:
nirB
annotation not available (847 aa)
  0.999
narK
annotation not available (465 aa)
 
  0.968
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (457 aa)
   
   
  0.967
narU
annotation not available (462 aa)
 
  0.964
t0605
Periplasmic nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (828 aa)
 
 
  0.940
gltB
annotation not available (1486 aa)
   
 
  0.936
glnA
Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family (469 aa)
     
 
  0.921
napB
Periplasmic nitrate reductase, electron transfer subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family (149 aa)
     
 
  0.916
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (550 aa)
   
 
    0.915
t1178
NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia (447 aa)
       
    0.909
Your Current Organism:
Salmonella enterica CT18
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica CT18, Salmonella enterica Typhi, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (9%) [HD]