STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY0155Conserved hypothetical protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family. (142 aa)    
Predicted Functional Partners:
STY0156
Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
     
 0.921
yrfF
Putative membrane protein; Similar to Escherichia coli hypothetical 79.5 kDa protein in mrcA-pckA intergenic region YrfF SW:YRFF_ECOLI (P45800) (711 aa) fasta scores: E(): 0, 83.9% id in 710 aa, and to Proteus mirabilis UmoB TR:O86988 (EMBL:U66822) (702 aa) fasta scores: E(): 0, 39.2% id in 701 aa. This CDS contains a signal sequence and several transmembrane regions.
  
   
 0.796
STY0517
Conserved hypothetical protein; Orthologue of E. coli ybaJ (YBAJ_ECOLI); Fasta hit to YBAJ_ECOLI (124 aa), 95% identity in 124 aa overlap.
  
   
 0.775
STY1246
Putative lipoprotein; Orthologue of E. coli YCFL_ECOLI; Fasta hit to YCFL_ECOLI (125 aa), 81% identity in 125 aa overlap.
  
     0.772
STY1560
Putative secreted protein; Orthologue of E. coli YNFB_ECOLI; Fasta hit to YNFB_ECOLI (113 aa), 81% identity in 113 aa overlap; Belongs to the UPF0482 family.
  
     0.772
STY3262
Conserved hypothetical protein; Orthologue of E. coli yggN (YGGN_ECOLI); Fasta hit to YGGN_ECOLI (239 aa), 88% identity in 239 aa overlap.
  
     0.772
STY1662
Putative membrane protein; Orthologue of E. coli YDGK_ECOLI; Fasta hit to YDGK_ECOLI (146 aa), 83% identity in 146 aa overlap.
  
     0.770
STY3968
Putative lipoprotein; Orthologue of E. coli o135 (YIDQ_ECOLI); Fasta hit to YIDQ_ECOLI (135 aa), 84% identity in 109 aa overlap. Contains a possible N-terminal signal sequence.
  
     0.769
STY1186
Glucans biosynthesis protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
  
     0.767
STY1788
Putative membrane protein; Similar to Escherichia coli hypothetical 20.4 kDa protein in pfkB-cedA intergenic region yniB SW:YNIB_ECOLI (P76208) (178 aa) fasta scores: E(): 0, 83.7% id in 178 aa, and to Yersinia pestis putative yfeABCD regulator YfeE yfeE SW:YFEE_YERPE (Q56956) (184 aa) fasta scores: E(): 0, 67.4% id in 181 aa; Orthologue of E. coli YNIB_ECOLI; Fasta hit to YNIB_ECOLI (178 aa), 84% identity in 178 aa overlap.
  
     0.764
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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