STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phnUProbable membrane component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). Belongs to the binding-protein-dependent transport system permease family. (289 aa)    
Predicted Functional Partners:
phnV
Probable membrane component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). Belongs to the binding-protein-dependent transport system permease family.
 
 
  0.989
phnS
Probable periplasmic binding component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import; Belongs to the bacterial solute-binding protein 1 family.
 
  
  0.988
phnT
Probable ATP-binding component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system (By similarity).
 
  
  0.987
STY2678
Sulphate transport ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
 
  
 0.839
STY3808
Periplasmic sulphate binding protein; Fasta hit to CYSP_ECOLI (338 aa), 46% identity in 323 aa overlap; Orthologue of E. coli sbp (SUBI_ECOLI); Fasta hit to SUBI_ECOLI (329 aa), 94% identity in 329 aa overlap.
 
  
 0.812
STY2681
Similar to Salmonella typhimurium thiosulphate-binding protein precursor cysP SW:CYSP_SALTY (P41031) (338 aa) fasta scores: E(): 0, 97.3% id in 338 aa; Fasta hit to SUBI_ECOLI (329 aa), 47% identity in 320 aa overlap; Orthologue of E. coli cysP (CYSP_ECOLI); Fasta hit to CYSP_ECOLI (338 aa), 94% identity in 337 aa overlap.
 
  
 0.797
STY2679
Sulphate transport system permease protein CysW; Fasta hit to CYST_ECOLI (277 aa), 37% identity in 259 aa overlap; Orthologue of E. coli cysW (CYSW_ECOLI); Fasta hit to CYSW_ECOLI (291 aa), 97% identity in 291 aa overlap.
 
  
0.791
cysD
ATP sulfurylase (ATP:sulfate adenyltransferase); Orthologue of E. coli cysD (CYSD_ECOLI); Fasta hit to CYSD_ECOLI (302 aa), 97% identity in 302 aa overlap.
  
  
 0.722
cysN
ATP sulfurylase (ATP:sulfate adenyltransferase) subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.720
cysC
Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.678
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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