| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STY0052 | STY0493 | gene:17584100 | gene:17584515 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 0.532 |
| STY0052 | STY1771 | gene:17584100 | gene:17585705 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | Integration host factor alpha-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. | 0.532 |
| STY0052 | STY2860 | gene:17584100 | gene:17586756 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.985 |
| STY0052 | STY3464 | gene:17584100 | gene:17587314 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.997 |
| STY0052 | STY3715 | gene:17584100 | gene:17587575 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | Histone like DNA-binding protein HU-alpha (NS2) (HU-2); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 0.532 |
| STY0492 | STY0493 | gene:17584514 | gene:17584515 | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 0.520 |
| STY0492 | STY3778 | gene:17584514 | gene:17587642 | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | Heat shock protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. Belongs to the peptidase T1B family. HslV subfamily. | 0.911 |
| STY0492 | STY3779 | gene:17584514 | gene:17587643 | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | Heat shock protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.932 |
| STY0493 | STY0052 | gene:17584515 | gene:17584100 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.532 |
| STY0493 | STY0492 | gene:17584515 | gene:17584514 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.520 |
| STY0493 | STY1661 | gene:17584515 | gene:17585596 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | Conserved hypothetical protein; Binds to H-NS and modified the range of genes it silences; H- NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer. Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity). The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity); Belongs to the Hha/YmoA/Cnu family. | 0.562 |
| STY0493 | STY1771 | gene:17584515 | gene:17585705 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | Integration host factor alpha-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. | 0.566 |
| STY0493 | STY2860 | gene:17584515 | gene:17586756 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.679 |
| STY0493 | STY3464 | gene:17584515 | gene:17587314 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.530 |
| STY0493 | STY3715 | gene:17584515 | gene:17587575 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | Histone like DNA-binding protein HU-alpha (NS2) (HU-2); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 0.618 |
| STY0493 | STY3778 | gene:17584515 | gene:17587642 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | Heat shock protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. Belongs to the peptidase T1B family. HslV subfamily. | 0.588 |
| STY0493 | STY3779 | gene:17584515 | gene:17587643 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | Heat shock protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.569 |
| STY0493 | acpP | gene:17584515 | gene:17585200 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.656 |
| STY1661 | STY0493 | gene:17585596 | gene:17584515 | Conserved hypothetical protein; Binds to H-NS and modified the range of genes it silences; H- NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer. Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity). The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity); Belongs to the Hha/YmoA/Cnu family. | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 0.562 |
| STY1661 | STY3778 | gene:17585596 | gene:17587642 | Conserved hypothetical protein; Binds to H-NS and modified the range of genes it silences; H- NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer. Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity). The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity); Belongs to the Hha/YmoA/Cnu family. | Heat shock protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. Belongs to the peptidase T1B family. HslV subfamily. | 0.561 |
