STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY0689Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. (377 aa)    
Predicted Functional Partners:
STY0690
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
   
 
 0.911
pbpA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 0.829
STY0692
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
     
 0.746
STY0693
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
 
 0.737
STY1419
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap.
   
   0.733
STY2098
Conserved hypothetical protein; Unknown function. Similar to many bacterial hypothetical proteins; Orthologue of E. coli yebA (YEBA_ECOLI); Fasta hit to YEBA_ECOLI (419 aa), 92% identity in 419 aa overlap.
    
 
 0.725
mviN
Virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
     
 0.719
slt
Similar to Escherichia coli soluble lytic murein transglycosylase precursor slt or sltY SW:SLT_ECOLI (P03810; P76820) (645 aa) fasta scores: E(): 0, 91.2% id in 627 aa.
 
   
 0.714
STY0688
D-alanine carboxypeptidase; Fasta hit to DACC_ECOLI (400 aa), 60% identity in 401 aa overlap; Fasta hit to DACD_ECOLI (388 aa), 48% identity in 390 aa overlap; Orthologue of E. coli dacA (DACA_ECOLI); Fasta hit to DACA_ECOLI (403 aa), 95% identity in 403 aa overlap; Belongs to the peptidase S11 family.
  
  
 0.679
STY2218
Putative exported protein; Similar to Salmonella typhimurium protein erfK/srfK precursor SW:ERFK_SALTY (P40680) (309 aa) fasta scores: E(): 0, 99.0% id in 309 aa. Contains probable N-terminal signal sequence; Fasta hit to YNHG_ECOLI (334 aa), 47% identity in 288 aa overlap; Fasta hit to YCFS_ECOLI (320 aa), 48% identity in 307 aa overlap; Fasta hit to YBIS_ECOLI (306 aa), 66% identity in 283 aa overlap; Orthologue of E. coli erfK (ERFK_ECOLI); Fasta hit to ERFK_ECOLI (310 aa), 79% identity in 305 aa overlap.
      
 0.646
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (16%) [HD]