STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
STY0747Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (559 aa)    
Predicted Functional Partners:
STY0745
Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 0.999
STY0746
Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
 0.999
STY0744
Sensor protein KdpD; Orthologue of E. coli kdpD (KDPD_ECOLI); Fasta hit to KDPD_ECOLI (894 aa), 89% identity in 902 aa overlap.
 
  
 0.993
STY0743
KDP operon transcriptional regulatory protein; Fasta hit to TORR_ECOLI (230 aa), 31% identity in 218 aa overlap; Fasta hit to BAER_ECOLI (240 aa), 34% identity in 224 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 36% identity in 219 aa overlap; Fasta hit to YEDW_ECOLI (239 aa), 33% identity in 221 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 34% identity in 231 aa overlap; Fasta hit to YGIX_ECOLI (219 aa), 34% identity in 220 aa overlap; Fasta hit to ARCA_ECOLI (238 aa), 31% identity in 228 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 30% identity in 227 aa overlap; Fasta hit to PHOB [...]
 
  
 0.978
STY3898
Membrane transport protein; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family.
   
  
 0.804
copS
Histidine kinase; Member of a two-component regulatory system.
  
  
 0.578
STY1570
Putative ABC transporter membrane protein; Similar to Bacillus subtilis glycine betaine/carnitine/choline transport system permease protein OpucB SW:OPCB_BACSU (O34878) (217 aa) fasta scores: E(): 3.3e-25, 40.8% id in 196 aa; Paralogue of E. coli YehW (YEHW_ECOLI); Fasta hit to YEHW_ECOLI (243 aa), 43% identity in 200 aa overlap.
      
 0.465
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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