STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY0754Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (244 aa)    
Predicted Functional Partners:
STY0752
Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.
 
 0.999
STY0753
Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.
 
 0.999
STY0626
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
     
  0.900
STY2944
Gamma-glutamylcysteine synthetase; Similar to Salmonella typhimurium LT2 glutamate--cysteine ligase SW:GSH1_SALTY (O68838) (518 aa) fasta scores: E(): 0, 98.6% id in 518 aa; Orthologue of E. coli gshA (GSH1_ECOLI); Fasta hit to GSH1_ECOLI (518 aa), 93% identity in 518 aa overlap; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
ggt
Similar to Escherichia coli gamma-glutamyltranspeptidase precursor ggt SW:GGT_ECOLI (P18956) (580 aa) fasta scores: E(): 0, 91.4% id in 580 aa, and to Helicobacter pylori J99 gamma-glutamyltranspeptidase ggt TR:Q9ZK95 (EMBL:AE001532) (567 aa) fasta scores: E(): 0, 52.7% id in 537 aa. Contains N-terminal signal sequence, probable secreted protein.
     
  0.900
STY1159
Proline dehydrogenase (proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
   
 
  0.897
STY3874
Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
   
 
  0.802
STY1815
NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
     
  0.800
STY3510
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 95.4% id in 1486 aa and to Pseudomonas aeruginosa glutamate synthase large subunit GltB TR:P95456 (EMBL:U81261) (1482 aa) fasta scores: E(): 0, 60.9% id in 1476 aa.
     
  0.800
STY3511
Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap.
     
  0.800
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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