STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutIImidazolonepropionase; Similar to Yersinia pestis imidazolonepropionase hutI SW:HUTI_YERPE (Q9ZC74) (406 aa) fasta scores: E(): 0, 50.0% id in 400 aa, and to Rhizobium meliloti imidazolonepropionase hutI SW:HUTI_RHIME (O31196) (369 aa) fasta scores: E(): 0, 51.8% id in 340 aa; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (407 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 
 0.998
hutG
Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
 
 0.997
hutH
Similar to Pseudomonas putida histidine ammonia-lyase SW:HUTH_PSEPU (P21310) (509 aa) fasta scores: E(): 0, 77.4% id in 500 aa, and to Rhizobium meliloti histidine ammonia-lyase SW:HUTH_RHIME () (511 aa) fasta scores: E(): 0, 52.6% id in 498 aa; Belongs to the PAL/histidase family.
 
  
 0.995
hutC
Similar to Klebsiella aerogenes histidine utilization repressor hutC SW:HUTC_KLEAE (P12380) (241 aa) fasta scores: E(): 0, 78.8% id in 241 aa, and to Pseudomonas putida histidine utilization repressor hutC SW:HUTC_PSEPU (P22773) (248 aa) fasta scores: E(): 0, 63.5% id in 230 aa.
 
  
 0.977
STY2624
VacJ lipoprotein precursor; Orthologue of E. coli vacJ (VACJ_ECOLI); Fasta hit to VACJ_ECOLI (251 aa), 94% identity in 251 aa overlap.
      
 0.810
STY3937
Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
      
 0.502
STY3238
Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.
  
  
 0.473
STY0819
Similar to Erwinia chrysanthemi pectinesterase b precursor pemB SW:PMEB_ERWCH (Q47474) (433 aa) fasta scores: E(): 0, 44.8% id in 429 aa, and to Escherichia coli hypothetical 46.1 kDa protein in modc-bioa intergenic region precursor. putative lipoprotein ybhc precursor SW:YBHC_ECOLI () (427 aa) fasta scores: E(): 0, 86.7% id in 427 aa. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site; Orthologue of E. coli ybhC (YBHC_ECOLI); Fasta hit to YBHC_ECOLI (427 aa), 87% identity in 427 aa overlap.
       0.465
STY3936
Putative membrane transport protein; Similar to Escherichia coli bicyclomycin resistance protein BicR SW:BCR_ECOLI (P28246) (396 aa) fasta scores: E(): 1.5e-20, 25.5% id in 381 aa. Contains multiple possible membrane spanning hydrophobic domains; Orthologue of E. coli yidY (YIDY_ECOLI); Fasta hit to YIDY_ECOLI (391 aa), 78% identity in 393 aa overlap.
      
 0.420
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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