STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1129Putative exported protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). (136 aa)    
Predicted Functional Partners:
copS
Histidine kinase; Member of a two-component regulatory system.
 
     0.631
STY3558
Putative membrane protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. MsrQ prov [...]
   
    0.572
copR
Response regulator; Fasta hit to TORR_ECOLI (230 aa), 34% identity in 229 aa overlap; Fasta hit to BAER_ECOLI (240 aa), 32% identity in 224 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 52% identity in 227 aa overlap; Fasta hit to RSTA_ECOLI (242 aa), 34% identity in 228 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 34% identity in 233 aa overlap; Fasta hit to YGIX_ECOLI (219 aa), 38% identity in 220 aa overlap; Fasta hit to ARCA_ECOLI (238 aa), 33% identity in 228 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 39% identity in 227 aa overlap; Fasta hit to PHOB_ECOLI (229 aa), 37% identi [...]
       0.555
STY1157
Putative transcriptional regulator; Orthologue of E. coli YCDC_ECOLI; Fasta hit to YCDC_ECOLI (212 aa), 83% identity in 212 aa overlap.
 
     0.554
STY3557
Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The [...]
  
   0.542
allC
Similar to Escherichia coli allantoate amidohydrolase allc or glxb7 SW:ALLC_ECOLI (P77425) (411 aa) fasta scores: E(): 0, 88.1% id in 411 aa, and to Bacillus subtilis probable allantoate amidohydrolase yurH SW:ALLC_BACSU (O32149) (412 aa) fasta scores: E(): 0, 47.8% id in 404 aa; Orthologue of E. coli YLBB_ECOLI; Fasta hit to YLBB_ECOLI (411 aa), 88% identity in 411 aa overlap.
 
   
 0.524
STY0574
Similar to Escherichia coli hypothetical 28.7 kDa protein in gip-fdra intergenic region (glxB6 TR:O54410 (EMBL:AE000157)) SW:YLBA_ECOLI (P75713) (261 aa) fasta scores: E(): 0, 92.3% id in 261 aa; Orthologue of E. coli YLBA_ECOLI; Fasta hit to YLBA_ECOLI (261 aa), 92% identity in 261 aa overlap.
 
   
 0.440
allB
Putative allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
 
   
 0.431
STY4046
Putative purine permease; Similar to Escherichia coli hypothetical 48.9 kDa protein in gltS-selC intergenic region putative purine permease SW:YICE_ECOLI (P27432) (463 aa) fasta scores: E(): 0, 95.2% id in 462 aa, and to Bacillus subtilis xanthine permease pbuX SW:PBUX_BACSU (P42086) (438 aa) fasta scores: E(): 2.5e-31, 31.1% id in 431 aa.
 
  
 0.420
STY1413
Hypothetical protein; No significant database matches.
   
 0.413
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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