STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1191Putative membrane transport protein; Similar to Streptococcus pneumoniae multi-drug resistance efflux pump PmraATR:Q9ZEX9 (EMBL:AJ007367) (399 aa) fasta scores: E(): 0, 44.4% id in 390 aa; Orthologue of E. coli yceE (YCEE_ECOLI); Fasta hit to YCEE_ECOLI (408 aa), 90% identity in 403 aa overlap. (404 aa)    
Predicted Functional Partners:
STY3936
Putative membrane transport protein; Similar to Escherichia coli bicyclomycin resistance protein BicR SW:BCR_ECOLI (P28246) (396 aa) fasta scores: E(): 1.5e-20, 25.5% id in 381 aa. Contains multiple possible membrane spanning hydrophobic domains; Orthologue of E. coli yidY (YIDY_ECOLI); Fasta hit to YIDY_ECOLI (391 aa), 78% identity in 393 aa overlap.
  
  
 0.818
STY4874
Putative sugar transport protein; Similar to Escherichia coli hypothetical protein YjiO yjiO SW:YJIO_ECOLI (P39386) (410 aa) fasta scores: E(): 0, 86.0% id in 408 aa and to Escherichia coli multidrug translocase mdfA SW:MDFA_ECOLI (Q46966) (410 aa) fasta scores: E(): 0, 40.2% id in 386 aa.
  
  
 0.813
STY1204
Putative membrane transporter; Orthologue of E. coli YCEL_ECOLI; Fasta hit to YCEL_ECOLI (402 aa), 91% identity in 402 aa overlap.
      
 0.812
STY3981
Multidrug resistance protein D; Orthologue of E. coli emrD (EMRD_ECOLI); Fasta hit to EMRD_ECOLI (396 aa), 93% identity in 394 aa overlap.
  
  
 0.792
STY1697
Hypothetical integral membrane protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
      
 0.581
STY1190
Acidic protein MsyB; Orthologue of E. coli msyB (MSYB_ECOLI); Fasta hit to MSYB_ECOLI (124 aa), 93% identity in 124 aa overlap.
       0.554
STY2339
Similar to efflux-system proteins e.g. Neisseria gonorrhoeae membrane fusion protein MtrC precursor mtrC SW:MTRC_NEIGO (P43505) (412 aa) fasta scores: E(): 4.8e-26, 32.7% id in 342 aa and Escherichia coli acriflavin resistance protein a precursor acrA or acrE SW:ACRA_ECOLI (P31223) (397 aa) fasta scores: E(): 5.5e-23, 28.9% id in 356 aa. Contains possible N-terminal membrane anchor; Fasta hit to ACRE_ECOLI (385 aa), 31% identity in 331 aa overlap; Orthologue of E. coli YEGM_ECOLI; Fasta hit to YEGM_ECOLI (415 aa), 83% identity in 415 aa overlap; Belongs to the membrane fusion protein ( [...]
      
 0.536
STY2340
Putative RND-family transporter protein; Fasta hit to YEGO_ECOLI (1025 aa), 50% identity in 1023 aa overlap; Orthologue of E. coli YEGN_ECOLI; Fasta hit to YEGN_ECOLI (1040 aa), 92% identity in 1040 aa overlap; Similar to many. Contains hydrophobic, probable membrane-spanning regions; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
    
 
 0.536
STY1838
Putative membrane protein; Similar to Escherichia coli hypothetical 15.3 kDa protein in gapA-rnd intergenic region yeaL SW:YEAL_ECOLI (P76240; O07965; O07967) (148 aa) fasta scores: E(): 0, 95.3% id in 148 aa, and to Haemophilus influenzae hypothetical protein Hi1074 hi1074 SW:YEAL_HAEIN (P44110) (150 aa) fasta scores: E(): 3.9e-24, 50.4% id in 141 aa.
  
     0.532
STY2940
Multidrug resistance protein A; Fasta hit to EMRK_ECOLI (387 aa), 50% identity in 377 aa overlap; Orthologue of E. coli emrA (EMRA_ECOLI); Fasta hit to EMRA_ECOLI (390 aa), 90% identity in 390 aa overlap.
   
 
 0.531
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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