STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1377Putative membrane protein; Orthologue of E. coli ycjF (YCJF_ECOLI); Fasta hit to YCJF_ECOLI (353 aa), 88% identity in 353 aa overlap. (353 aa)    
Predicted Functional Partners:
STY1376
Putative ATP-binding protein; Orthologue of E. coli YCJX_ECOLI; Fasta hit to YCJX_ECOLI (465 aa), 94% identity in 465 aa overlap.
 
  
 0.998
STY1374
Phage shock protein D; Orthologue of E. coli pspD (PSPD_ECOLI); Fasta hit to PSPD_ECOLI (73 aa), 88% identity in 72 aa overlap.
     
 0.887
STY1373
Phage shock protein C; Orthologue of E. coli pspC (PSPC_ECOLI); Fasta hit to PSPC_ECOLI (119 aa), 84% identity in 119 aa overlap.
 
   
 0.742
smp
Putative membrane protein; Similar to Escherichia coli smp protein precursor SW:SMP_ECOLI (P18838) (214 aa) fasta scores: E(): 0, 91.1% id in 214 aa.
  
     0.728
STY2811
Putative sensor kinase protein; C-terminal half shares similarity with e.g. Mycobacterium tuberculosis MtrB mtrB TR:Q50496 (EMBL:U14909) (567 aa) fasta scores: E(): 5.4e-15, 27.6% id in 301 aa and Pseudomonas aeruginosa alginate biosynthesis sensor protein KinB kinB TR:O34206 (EMBL:U97063) (595 aa) fasta scores: E(): 4.3e-14, 30.0% id in 273 aa; Orthologue of E. coli YFHK_ECOLI; Fasta hit to YFHK_ECOLI (496 aa), 87% identity in 460 aa overlap.
  
     0.699
STY1378
Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...]
   
 0.696
STY3527
Conserved hypothetical protein; Orthologue of E. coli yhcB (YHCB_ECOLI); Fasta hit to YHCB_ECOLI (134 aa), 96% identity in 132 aa overlap.
  
     0.664
STY2615
Penicillin-insensitive murein endopeptidase precursor; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family.
  
     0.660
STY1372
Phage shock protein B; Orthologue of E. coli pspB (PSPB_ECOLI); Fasta hit to PSPB_ECOLI (74 aa), 89% identity in 74 aa overlap.
 
   
 0.644
STY4045
Putative exported protein; Similar to Escherichia coli hypothetical 62.3 kDa protein in glts-selc intergenic region yicH SW:YICH_ECOLI (P31433) (569 aa) fasta scores: E(): 0, 79.9% id in 567 aa.
  
     0.557
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.