| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STY0231 | STY2616 | gene:17584265 | gene:17586513 | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.777 |
| STY0231 | aroD | gene:17584265 | gene:17585694 | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of Lys-170 at the active site; Belongs to the type-I 3-dehydroquinase family. | 0.791 |
| STY0639 | STY1327 | gene:17584652 | gene:17585288 | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.946 |
| STY0639 | STY2616 | gene:17584652 | gene:17586513 | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.887 |
| STY0639 | STY2854 | gene:17584652 | gene:17586750 | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | Chorismate mutase-P/prephenate dehydratase; Orthologue of E. coli pheA (PHEA_ECOLI); Fasta hit to PHEA_ECOLI (386 aa), 91% identity in 385 aa overlap. | 0.885 |
| STY0639 | STY3924 | gene:17584652 | gene:17587783 | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | Putative shikimate 5-dehydrogenase; Similar to Haemophilus influenzae hypothetical protein SW:YDIB_HAEIN () (271 aa) fasta scores: E(): 4.9e-27, 51.7% id in 267 aa, and in parts to several others including: Nicotiana tabacum dehydroquinate dehydratase/shikimate dehydrogenase precursor TR:Q42947 (EMBL:L32794) (579 aa) fasta scores: E(): 6.8e-07, 26.0% id in 289 aa. | 0.810 |
| STY0639 | aroD | gene:17584652 | gene:17585694 | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of Lys-170 at the active site; Belongs to the type-I 3-dehydroquinase family. | 0.840 |
| STY0639 | aroE | gene:17584652 | gene:17588224 | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.862 |
| STY0639 | menF | gene:17584652 | gene:17586440 | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.926 |
| STY1327 | STY0639 | gene:17585288 | gene:17584652 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | 0.946 |
| STY1327 | STY2616 | gene:17585288 | gene:17586513 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.994 |
| STY1327 | STY2854 | gene:17585288 | gene:17586750 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | Chorismate mutase-P/prephenate dehydratase; Orthologue of E. coli pheA (PHEA_ECOLI); Fasta hit to PHEA_ECOLI (386 aa), 91% identity in 385 aa overlap. | 0.988 |
| STY1327 | STY3924 | gene:17585288 | gene:17587783 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | Putative shikimate 5-dehydrogenase; Similar to Haemophilus influenzae hypothetical protein SW:YDIB_HAEIN () (271 aa) fasta scores: E(): 4.9e-27, 51.7% id in 267 aa, and in parts to several others including: Nicotiana tabacum dehydroquinate dehydratase/shikimate dehydrogenase precursor TR:Q42947 (EMBL:L32794) (579 aa) fasta scores: E(): 6.8e-07, 26.0% id in 289 aa. | 0.682 |
| STY1327 | aroB | gene:17585288 | gene:17588141 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.866 |
| STY1327 | aroD | gene:17585288 | gene:17585694 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of Lys-170 at the active site; Belongs to the type-I 3-dehydroquinase family. | 0.615 |
| STY1327 | aroE | gene:17585288 | gene:17588224 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.741 |
| STY1327 | aroK | gene:17585288 | gene:17588140 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.637 |
| STY1327 | menF | gene:17585288 | gene:17586440 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.958 |
| STY2616 | STY0231 | gene:17586513 | gene:17584265 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. | 0.777 |
| STY2616 | STY0639 | gene:17586513 | gene:17584652 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Isochorismate synthase EntC; Orthologue of E. coli entC (ENTC_ECOLI); Fasta hit to ENTC_ECOLI (391 aa), 85% identity in 388 aa overlap. | 0.887 |
