STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1898Putative regulator; Required for maximal expression of sirC, not required to invade host cells (By similarity). (269 aa)    
Predicted Functional Partners:
STY1899
Putative regulator; Required for maximal expression of sirC, not required to invade host cells; Belongs to the SirB2 family.
  
  
 0.984
hemK
HemK protein, putative protoporphyrinogen oxidase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.869
prfA
Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.869
STY0271
RcsF protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.742
STY1897
2-dehydro-3-deoxyphosphooctonate aldolase; Orthologue of E. coli kdsA (KDSA_ECOLI); Fasta hit to KDSA_ECOLI (284 aa), 94% identity in 282 aa overlap; Belongs to the KdsA family.
       0.683
STY1902
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.675
STY1094
Conserved hypothetical protein; Orthologue of E. coli YCCR_ECOLI; Fasta hit to YCCR_ECOLI (209 aa), 75% identity in 199 aa overlap.
  
     0.665
STY3138
Prepilin peptidase dependent protein A precursor; Orthologue of E. coli ppdA (PPDA_ECOLI); Fasta hit to PPDA_ECOLI (156 aa), 67% identity in 155 aa overlap.
  
     0.659
STY0189
Conserved hypothetical protein; Orthologue of E. coli yacC (YACC_ECOLI); Fasta hit to YACC_ECOLI (115 aa), 96% identity in 115 aa overlap.
  
     0.656
STY3215
Conserved hypothetical protein; Orthologue of E. coli ygfB (YGFB_ECOLI); Fasta hit to YGFB_ECOLI (194 aa), 93% identity in 194 aa overlap; Belongs to the UPF0149 family.
  
     0.656
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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