STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1909peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death. (202 aa)    
Predicted Functional Partners:
STY1910
Putative ATP/GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.917
STY4150
Conserved hypothetical protein; Similar to C-terminal region of Mycobacterium tuberculosis hypothetical protein Rv0918 TR:O05910 (EMBL:Z95210) (158 aa) fasta scores: E(): 1.6e-05, 37.8% id in 82 aa.
      
 0.814
STY4151
Putative acetyltransferase; Similar to Mycobacterium tuberculosis hypothetical protein Rv0919 TR:O05911 (EMBL:Z95210) (166 aa) fasta scores: E(): 8.5e-29, 50.3% id in 153 aa and Escherichia coli ORF79 protein from plasmid pB171 TR:Q9S0Z0 (EMBL:AB024946) (176 aa) fasta scores: E(): 1.2e-08, 28.1% id in 135 aa.
   
  
 0.806
prfA
Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
   
 0.770
STY0242
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
   
 0.731
STY2589
Shows weak similarity to putative amino acid transporters e.g. Shigella flexneri amino acid antiporter xasA or gadC SW:XASA_SHIFL (Q54152) (511 aa) fasta scores: E(): 1.8e-29, 25.3% id in 467 aa. Contains hydrophobic, probable membrane-spanning regions.
     
 0.723
STY2751
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.672
STY3197
Peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
  
 0.632
STY1772
phenylalanyl-tRNA synthetase beta chain; Orthologue of E. coli pheT (SYFB_ECOLI); Fasta hit to SYFB_ECOLI (795 aa), 92% identity in 795 aa overlap; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.629
STY3482
50S ribosomal subunit protein L27; Orthologue of E. coli rpmA (RL27_ECOLI); Fasta hit to RL27_ECOLI (84 aa), 95% identity in 84 aa overlap; Belongs to the bacterial ribosomal protein bL27 family.
 
  
 0.626
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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