STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1946Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (88 aa)    
Predicted Functional Partners:
STY1945
Septum site determining protein; Orthologue of E. coli minD (MIND_ECOLI); Fasta hit to MIND_ECOLI (269 aa), 97% identity in 269 aa overlap.
 
 
 0.998
STY1944
Septum site determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
  
 0.945
STY2828
Signal peptidase I; Identical to Salmonella typhimurium signal peptidase I lepB SW:LEP_SALTY (P23697) (324 aa) fasta scores: E(): 0, 100.0% id in 324 aa; Orthologue of E. coli lepB (LEP_ECOLI); Fasta hit to LEP_ECOLI (324 aa), 94% identity in 324 aa overlap; Belongs to the peptidase S26 family.
   
    0.943
STY1967
Cold shock-like protein CspC; Orthologue of E. coli cspC (CSPC_ECOLI); Fasta hit to CSPC_ECOLI (68 aa), 100% identity in 68 aa overlap.
   
    0.805
STY3351
Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.796
STY1968
Conserved hypothetical protein; Orthologue of E. coli YOBF_ECOLI; Fasta hit to YOBF_ECOLI (47 aa), 94% identity in 47 aa overlap.
   
    0.787
STY0264
Conserved hypothetical protein; Orthologue of E. coli yaeQ (YAEQ_ECOLI); Fasta hit to YAEQ_ECOLI (181 aa), 89% identity in 181 aa overlap.
   
    0.746
STY1226
Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
  
    0.687
STY2580
Conserved hypothetical protein; Orthologue of E. coli YFCH_ECOLI; Fasta hit to YFCH_ECOLI (297 aa), 87% identity in 297 aa overlap.
   
  
 0.610
STY1904
Outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
    0.605
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.