node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0013 | STY1975 | gene:17584068 | gene:17585891 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | 0.468 |
STY0013 | STY2868 | gene:17584068 | gene:17586764 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Heat shock protein GrpE (heat shock protein b25.3) (hsp24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the rea [...] | 0.975 |
STY0013 | STY3474 | gene:17584068 | gene:17587326 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.702 |
STY0013 | ybbN | gene:17584068 | gene:17584569 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Thioredoxin-like protein; Similar to Escherichia coli hypothetical 33.1 kDa protein in usha-tesa intergenic region ybbN SW:YBBN_ECOLI (P77395) (296 aa) fasta scores: E(): 0, 93.8% id in 290 aa, and to Alicyclobacillus acidocaldarius thioredoxin trxA SW:THIO_ALIAC (P80579) (105 aa) fasta scores: E(): 1.5e-07, 35.6% id in 104 aa, and to Escherichia coli thioredoxin 2 trxC SW:THI2_ECOLI (P33636; P76593; P77000; P77001) (139 aa) fasta scores: E(): 1e-06, 29.5% id in 105 aa. Note that the redox-active disulphide pair is not conserved; Orthologue of E. coli YBBN_ECOLI; Fasta hit to YBBN_ECOL [...] | 0.594 |
STY0231 | STY1975 | gene:17584265 | gene:17585891 | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | 0.492 |
STY0231 | STY3811 | gene:17584265 | gene:17587675 | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. | Extracytoplasmic stress protein for protein-mediated toxicities; Similar to Escherichia coli periplasmic protein CpxP precursor SW:CPXP_ECOLI () (166 aa) fasta scores: E(): 0, 88.6% id in 166 aa. Contains a possible N-terminal signal sequence; Fasta hit to SPY_ECOLI (161 aa), 32% identity in 159 aa overlap. | 0.634 |
STY0231 | kefB | gene:17584265 | gene:17588169 | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. | Glutathione-regulated potassium-efflux system protein (K(+)/H(+)antiporter); Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | 0.558 |
STY1112 | STY1975 | gene:17585090 | gene:17585891 | Putative membrane protein; Orthologue of E. coli yccA (YCCA_ECOLI); Fasta hit to YCCA_ECOLI (219 aa), 95% identity in 219 aa overlap; Belongs to the BI1 family. | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | 0.655 |
STY1312 | STY1975 | gene:17585273 | gene:17585891 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | 0.474 |
STY1312 | kefB | gene:17585273 | gene:17588169 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Glutathione-regulated potassium-efflux system protein (K(+)/H(+)antiporter); Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | 0.624 |
STY1975 | STY0013 | gene:17585891 | gene:17584068 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.468 |
STY1975 | STY0231 | gene:17585891 | gene:17584265 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. | 0.492 |
STY1975 | STY1112 | gene:17585891 | gene:17585090 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Putative membrane protein; Orthologue of E. coli yccA (YCCA_ECOLI); Fasta hit to YCCA_ECOLI (219 aa), 95% identity in 219 aa overlap; Belongs to the BI1 family. | 0.655 |
STY1975 | STY1312 | gene:17585891 | gene:17585273 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.474 |
STY1975 | STY1976 | gene:17585891 | gene:17585892 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Tail-specific protease precursor; Orthologue of E. coli prc (PRC_ECOLI); Fasta hit to PRC_ECOLI (682 aa), 93% identity in 682 aa overlap; Belongs to the peptidase S41A family. | 0.479 |
STY1975 | STY2868 | gene:17585891 | gene:17586764 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Heat shock protein GrpE (heat shock protein b25.3) (hsp24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the rea [...] | 0.544 |
STY1975 | STY3474 | gene:17585891 | gene:17587326 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.732 |
STY1975 | STY3811 | gene:17585891 | gene:17587675 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Extracytoplasmic stress protein for protein-mediated toxicities; Similar to Escherichia coli periplasmic protein CpxP precursor SW:CPXP_ECOLI () (166 aa) fasta scores: E(): 0, 88.6% id in 166 aa. Contains a possible N-terminal signal sequence; Fasta hit to SPY_ECOLI (161 aa), 32% identity in 159 aa overlap. | 0.532 |
STY1975 | kefB | gene:17585891 | gene:17588169 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Glutathione-regulated potassium-efflux system protein (K(+)/H(+)antiporter); Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | 0.653 |
STY1975 | ybbN | gene:17585891 | gene:17584569 | Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family. | Thioredoxin-like protein; Similar to Escherichia coli hypothetical 33.1 kDa protein in usha-tesa intergenic region ybbN SW:YBBN_ECOLI (P77395) (296 aa) fasta scores: E(): 0, 93.8% id in 290 aa, and to Alicyclobacillus acidocaldarius thioredoxin trxA SW:THIO_ALIAC (P80579) (105 aa) fasta scores: E(): 1.5e-07, 35.6% id in 104 aa, and to Escherichia coli thioredoxin 2 trxC SW:THI2_ECOLI (P33636; P76593; P77000; P77001) (139 aa) fasta scores: E(): 1e-06, 29.5% id in 105 aa. Note that the redox-active disulphide pair is not conserved; Orthologue of E. coli YBBN_ECOLI; Fasta hit to YBBN_ECOL [...] | 0.474 |