STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2121Flagellar protein FlhE precursor; Not essential for flagellar formation and function. (130 aa)    
Predicted Functional Partners:
flhB
Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
  
  
 0.947
STY2122
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.928
STY1221
Flagellar protein FlgJ; Orthologue of E. coli flgJ (FLGJ_ECOLI); Fasta hit to FLGJ_ECOLI (313 aa), 83% identity in 316 aa overlap.
  
  
 0.912
STY1419
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap.
    
   0.886
STY2186
Flagellar protein FliO; Identical to Salmonella typhimurium flagellar protein FliO fliO or flbD or flaP SW:FLIO_SALTY (P54699) (125 aa) fasta scores: E(): 0, 100.0% id in 125 aa. Contains hydrophobic, probable membrane-spanning region; Orthologue of E. coli fliO (FLIO_ECOLI); Fasta hit to FLIO_ECOLI (101 aa), 71% identity in 104 aa overlap.
  
  
 0.787
STY1211
Negative regulator of flagellin synthesis (anti-sigma factor); Orthologue of E. coli flgM (FLGM_ECOLI); Fasta hit to FLGM_ECOLI (97 aa), 80% identity in 96 aa overlap.
  
  
 0.781
yrfF
Putative membrane protein; Similar to Escherichia coli hypothetical 79.5 kDa protein in mrcA-pckA intergenic region YrfF SW:YRFF_ECOLI (P45800) (711 aa) fasta scores: E(): 0, 83.9% id in 710 aa, and to Proteus mirabilis UmoB TR:O86988 (EMBL:U66822) (702 aa) fasta scores: E(): 0, 39.2% id in 701 aa. This CDS contains a signal sequence and several transmembrane regions.
  
   
 0.773
STY3407
Putative exported protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.749
STY4419
Putative lipoprotein; Similar to Escherichia coli hypothetical 25.0 kDa lipoprotein in pgi-xylE intergenic region YjbF SW:YJBF_ECOLI (P32687) (222 aa) fasta scores: E(): 0, 86.7% id in 211 aa, and to Escherichia coli hypothetical 24.3 kDa lipoprotein in appA-cspH intergenic region YmcC precursor SW:YMCC_ECOLI (P75884) (214 aa) fasta scores: E(): 8.9e-30, 38.5% id in 213 aa. Putative N-terminal lipoprotein attachment site.
  
     0.742
cld
Similar to Salmonella typhimurium chain length determinant protein wzzB or cld or rol SW:WZZB_SALTY (Q04866) (327 aa) fasta scores: E(): 0, 99.1% id in 327 aa. Contains hydrophobic, probable membrane-spanning regions; Orthologue of E. coli WZB1_ECOLI; Fasta hit to WZB1_ECOLI (326 aa), 72% identity in 326 aa overlap.
  
     0.734
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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