STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2266Putative DNA gyrase inhibitory protein; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. (155 aa)    
Predicted Functional Partners:
STY2088
Conserved hypothetical protein; Orthologue of E. coli yebG (YEBG_ECOLI); Fasta hit to YEBG_ECOLI (96 aa), 78% identity in 96 aa overlap.
   
  
 0.812
STY0538
Fosmidomycin resistance protein; Orthologue of E. coli fsr (FSR_ECOLI); Fasta hit to FSR_ECOLI (406 aa), 93% identity in 405 aa overlap.
      
 0.810
ybfE
Conserved hypothetical protein; Orthologue of E. coli YBFE_ECOLI; Fasta hit to YBFE_ECOLI (120 aa), 91% identity in 97 aa overlap. Shorter than ybfE at the N-terminus.
      
 0.810
STY4178
Conserved hypothetical protein; Orthologue of E. coli yhjS (YHJS_ECOLI); Fasta hit to YHJS_ECOLI (523 aa), 80% identity in 519 aa overlap.
  
     0.761
STY4900
Probable regulatory protein. Contains helix-turn-helix motif, residues 170-191, score 1107 (+2.96 SD). Similar to Escherichia coli hypothetical 27.0 kDa protein in dnaT-bglJ intergenic region YjjQ SW:YJJQ_ECOLI (P39403) (241 aa) fasta scores: E(): 0, 66.5% id in 242 aa, and to Erwinia amylovora response regulator HrpY TR:Q9X3S9 (EMBL:AF083877) (213 aa) fasta scores: E(): 0.00011, 28.8% id in 163 aa.
  
     0.752
STY1421
Heat shock protein; Orthologue of E. coli hslJ (HSLJ_ECOLI); Fasta hit to HSLJ_ECOLI (140 aa), 70% identity in 138 aa overlap.
  
     0.732
STY0819
Similar to Erwinia chrysanthemi pectinesterase b precursor pemB SW:PMEB_ERWCH (Q47474) (433 aa) fasta scores: E(): 0, 44.8% id in 429 aa, and to Escherichia coli hypothetical 46.1 kDa protein in modc-bioa intergenic region precursor. putative lipoprotein ybhc precursor SW:YBHC_ECOLI () (427 aa) fasta scores: E(): 0, 86.7% id in 427 aa. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site; Orthologue of E. coli ybhC (YBHC_ECOLI); Fasta hit to YBHC_ECOLI (427 aa), 87% identity in 427 aa overlap.
  
   
 0.731
STY1454
Putative transferase; Orthologue of E. coli P76100; Fasta hit to P76100 (326 aa), 66% identity in 326 aa overlap.
  
     0.680
STY2265
Putative membrane protein; Similar to Neisseria meningitidis putative integral membrane protein NMA0079 TR:Q9JX36 (EMBL:AL162752) (375 aa) fasta scores: E(): 4.7e-20, 27.3% id in 352 aa and Neisseria meningitidis hypothetical protein NMB0188 TR:Q9K1G5 (EMBL:AE002376) (375 aa) fasta scores: E(): 6.3e-20, 27.0% id in 352 aa. N-terminal half contains hydrophobic, possible membrane-spanning regions; Orthologue of E. coli yeeA (YEEA_ECOLI); Fasta hit to YEEA_ECOLI (352 aa), 78% identity in 352 aa overlap.
 
  
 0.662
STY0488
BolA protein; Orthologue of E. coli bolA (BOLA_ECOLI); Fasta hit to BOLA_ECOLI (105 aa), 92% identity in 105 aa overlap; Belongs to the BolA/IbaG family.
      
 0.660
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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