STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2341Putative RND-family transporter protein; Fasta hit to YEGN_ECOLI (1040 aa), 50% identity in 1021 aa overlap; Orthologue of E. coli YEGO_ECOLI; Fasta hit to YEGO_ECOLI (1025 aa), 92% identity in 1025 aa overlap; Similar to many. Contains hydrophobic, probable membrane-spanning regions; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. (1026 aa)    
Predicted Functional Partners:
STY2339
Similar to efflux-system proteins e.g. Neisseria gonorrhoeae membrane fusion protein MtrC precursor mtrC SW:MTRC_NEIGO (P43505) (412 aa) fasta scores: E(): 4.8e-26, 32.7% id in 342 aa and Escherichia coli acriflavin resistance protein a precursor acrA or acrE SW:ACRA_ECOLI (P31223) (397 aa) fasta scores: E(): 5.5e-23, 28.9% id in 356 aa. Contains possible N-terminal membrane anchor; Fasta hit to ACRE_ECOLI (385 aa), 31% identity in 331 aa overlap; Orthologue of E. coli YEGM_ECOLI; Fasta hit to YEGM_ECOLI (415 aa), 83% identity in 415 aa overlap; Belongs to the membrane fusion protein ( [...]
 
 0.999
STY2340
Putative RND-family transporter protein; Fasta hit to YEGO_ECOLI (1025 aa), 50% identity in 1023 aa overlap; Orthologue of E. coli YEGN_ECOLI; Fasta hit to YEGN_ECOLI (1040 aa), 92% identity in 1040 aa overlap; Similar to many. Contains hydrophobic, probable membrane-spanning regions; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 
0.991
STY2342
Putative transporter protein; Fasta hit to YIEO_ECOLI (475 aa), 46% identity in 459 aa overlap; Orthologue of E. coli YEGB_ECOLI; Fasta hit to YEGB_ECOLI (471 aa), 86% identity in 469 aa overlap; Similar to many putative major facilitator family transporter proteins. Contains hydrophobic, probable membrane-spanning regions.
  
 
 0.981
STY2344
Putative two-component system response regulator; Fasta hit to TORR_ECOLI (230 aa), 37% identity in 231 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 35% identity in 223 aa overlap; Fasta hit to RSTA_ECOLI (242 aa), 33% identity in 228 aa overlap; Fasta hit to YGIX_ECOLI (219 aa), 35% identity in 222 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 37% identity in 241 aa overlap; Fasta hit to ARCA_ECOLI (238 aa), 32% identity in 233 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 37% identity in 225 aa overlap; Fasta hit to PHOB_ECOLI (229 aa), 40% identity in 224 aa overlap; Fasta hit to P [...]
  
  
 0.914
STY2343
Putative two-component system sensor kinase; Orthologue of E. coli baeS (BAES_ECOLI); Fasta hit to BAES_ECOLI (467 aa), 89% identity in 467 aa overlap.
  
  
 0.908
STY1805
Putative exported protein; Similar to Escherichia coli spheroplast protein Y precursor spy SW:SPY_ECOLI (P77754) (161 aa) fasta scores: E(): 0, 88.2% id in 161 aa, and to Escherichia coli periplasmic protein CpxP precursor. periplasmic protein CpxP precursor SW:CPXP_ECOLI () (166 aa) fasta scores: E(): 3.1e-08, 30.4% id in 148 aa; Fasta hit to CPXP_ECOLI (166 aa), 30% identity in 148 aa overlap.
   
    0.782
STY0520
Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.750
STY2940
Multidrug resistance protein A; Fasta hit to EMRK_ECOLI (387 aa), 50% identity in 377 aa overlap; Orthologue of E. coli emrA (EMRA_ECOLI); Fasta hit to EMRA_ECOLI (390 aa), 90% identity in 390 aa overlap.
 
   
 0.740
STY2941
Multidrug resistance protein B; Fasta hit to YIEO_ECOLI (475 aa), 33% identity in 424 aa overlap; Fasta hit to EMRY_ECOLI (512 aa), 63% identity in 506 aa overlap; Orthologue of E. coli emrB (EMRB_ECOLI); Fasta hit to EMRB_ECOLI (512 aa), 96% identity in 512 aa overlap; Belongs to the major facilitator superfamily.
  
 
 0.637
STY3572
Possible lipoprotein; Orthologue of E. coli yhdV (YHDV_ECOLI); Fasta hit to YHDV_ECOLI (73 aa), 99% identity in 73 aa overlap. Contains a possible N-terminal signal sequence.
   
    0.572
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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