STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
STY2521Putative MR-MLE-family protein; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR). (405 aa)    
Predicted Functional Partners:
STY2519
Putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 2-keto-3- deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde. Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily.
 
 
 0.975
STY2520
Putative transport protein; Similar to e.g. Agrobacterium vitis putative tartrate transporter ttuB SW:TUB3_AGRVI (P70786) (449 aa) fasta scores: E(): 0, 40.9% id in 421 aa. Contains hydrophobic, probable membrane-spanning regions; Orthologue of E. coli YFAV_ECOLI; Fasta hit to YFAV_ECOLI (429 aa), 92% identity in 429 aa overlap.
 
  
 0.831
STY2522
Similar to transcriptional regulators e.g. Erwinia chrysanthemi pectin degradation repressor protein KdgR kdgR SW:KDGR_ERWCH (P37728) (305 aa) fasta scores: E(): 6.2e-18, 29.6% id in 257 aa; Fasta hit to KDGR_ECOLI (263 aa), 31% identity in 257 aa overlap; Fasta hit to YJHI_ECOLI (262 aa), 32% identity in 251 aa overlap; Orthologue of E. coli YFAX_ECOLI; Fasta hit to YFAX_ECOLI (260 aa), 87% identity in 260 aa overlap.
 
   
 0.829
STY3831
Conserved hypothetical protein; Involved in the anomeric conversion of L-rhamnose.
     
 0.828
STY2120
Similar to Bacillus subtilis hypothetical protein yesR TR:O31521 (EMBL:Z99107) (344 aa) fasta scores: E(): 4.6e-32, 29.3% id in 317 aa and to Bacillus subtilis hypothetical protein yteR TR:O34559 (EMBL:AF008220) (373 aa) fasta scores: E(): 4.3e-09, 26.0% id in 334 aa.
  
     0.527
hpaX
Similar to Escherichia coli putative 4-hydroxyphenylacetate permease hpaX TR:Q46984 (EMBL:Z37980) fasta scores: E(): 0, 87.3% id in 458 aa.
  
  
 0.469
hpcH
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
 
  
 0.458
STY2523
Conserved hypothetical protein; Orthologue of E. coli P77808; Fasta hit to P77808 (400 aa), 88% identity in 397 aa overlap; Belongs to the CinA family.
       0.423
STY1385
Putative oxidoreductase; Similar to Zea mays isoflavone reductase homolog IrL irL SW:IFRH_MAIZE (P52580) (309 aa) fasta scores: E(): 3e-07, 24.6% id in 281 aa.
  
     0.419
STY1429
Conserved hypothetical protein; Orthologue of E. coli ydcF (YDCF_ECOLI); Fasta hit to YDCF_ECOLI (266 aa), 69% identity in 266 aa overlap.
  
     0.401
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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