STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2526Ais protein; Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core. (201 aa)    
Predicted Functional Partners:
STY2527
Putative lipopolysaccharide biosynthesis protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
  
  
 0.689
STY3755
Putative membrane protein; Orthologue of E. coli yijP (YIJP_ECOLI); Fasta hit to YIJP_ECOLI (577 aa), 89% identity in 577 aa overlap. The N-terminus contains possible membrane spanning hydrophobic domains.
      
 0.652
STY4492
Putative membrane protein; Similar to Salmonella typhimurium hypothetical 61.6 kDa protein in basS/pmrA-adiY intergenic region YjdB SW:YJDB_SALTY (P36555) (547 aa) fasta scores: E(): 0, 99.6% id in 547 aa, and to Escherichia coli hypothetical 61.7 kDa protein in basS-adiY intergenic region YjdB SW:YJDB_ECOLI (P30845) (547 aa) fasta scores: E(): 0, 82.3% id in 547 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein.
      
 0.619
STY3128
Membrane-bound lytic murein transglycosylase A precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
      
 0.586
STY2530
Conserved hypothetical protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
  
  
 0.498
pmrD
Identical to Salmonella typhimurium polymyxin B resistance protein PmrD SW:PMRD_SALTY (P37589) (85 aa) fasta scores: E(): 0, 100.0% id in 84 aa; Orthologue of E. coli pmrD (PMRD_ECOLI); Fasta hit to PMRD_ECOLI (88 aa), 60% identity in 79 aa overlap.
      
 0.475
STY2532
Putative membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.
       0.474
STY2533
Putative membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.
       0.474
STY2940
Multidrug resistance protein A; Fasta hit to EMRK_ECOLI (387 aa), 50% identity in 377 aa overlap; Orthologue of E. coli emrA (EMRA_ECOLI); Fasta hit to EMRA_ECOLI (390 aa), 90% identity in 390 aa overlap.
      
 0.469
pmrA
Two-component response regulator; Similar to Salmonella typhimurium transcriptional regulatory protein PmrA or BasR SW:BASR_SALTY (P36556) (222 aa) fasta scores: E(): 0, 98.6% id in 222 aa, and to Escherichia coli transcriptional regulatory protein BasR SW:BASR_ECOLI (P30843) (222 aa) fasta scores: E(): 0, 90.1% id in 222 aa.
      
 0.461
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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