STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2740Phosphoribosylformylglycinamidine cyclo-ligase; Orthologue of E. coli purM (PUR5_ECOLI); Fasta hit to PUR5_ECOLI (344 aa), 91% identity in 344 aa overlap. (345 aa)    
Predicted Functional Partners:
STY0581
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
 
 0.999
STY2592
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.999
STY2741
Phosphoribosylglycinamidine myltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.999
STY2812
Phosphoribosylformylglycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
 
 0.999
STY3710
Phosphoribosylglycineamide synthetase; Orthologue of E. coli purD (PUR2_ECOLI); Fasta hit to PUR2_ECOLI (429 aa), 94% identity in 429 aa overlap; Belongs to the GARS family.
  
 0.999
STY3709
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Orthologue of E. coli purH (PUR9_ECOLI); Fasta hit to PUR9_ECOLI (529 aa), 94% identity in 529 aa overlap.
 
  
 0.996
STY0582
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
  
 0.991
STY2725
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Orthologue of E. coli purC (PUR7_ECOLI); Fasta hit to PUR7_ECOLI (237 aa), 95% identity in 237 aa overlap; Belongs to the SAICAR synthetase family.
 
  
 0.991
STY2089
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
 
  
 0.959
STY2593
Colicin V production protein (DedE protein); Orthologue of E. coli cvpA (CVPA_ECOLI); Fasta hit to CVPA_ECOLI (162 aa), 96% identity in 161 aa overlap.
   
    0.952
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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