STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2834L-aspartate oxidase (quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate. (540 aa)    
Predicted Functional Partners:
STY0167
Nicotinate-nucleotide pyrophosphorylase; Orthologue of E. coli nadC (NADC_ECOLI); Fasta hit to NADC_ECOLI (296 aa), 86% identity in 295 aa overlap; Belongs to the NadC/ModD family.
  
 0.999
STY0797
Quinolinate synthetase A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
 
 0.999
aspA
Similar to Escherichia coli Aspartate ammonia-lyase aspA SW:ASPA_ECOLI (P04422) (478 aa) fasta scores: E(): 0, 97.1% id in 478 aa, and to Serratia marcescens Aspartate ammonia-lyase aspA SW:ASPA_SERMA (P33109) (478 aa) fasta scores: E(): 0, 89.7% id in 478 aa.
 
   
 0.914
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.914
STY0353
Possible hydrolase; Similar to many hypothetical proteins e.g. Escherichia coli hypothetical protein in agr operon TR:Q9R2E1 (EMBL:D83536) (259 aa) fasta scores: E(): 0, 82.0% id in 255 aa, and to Bacillus subtilis YkrU protein ykrU TR:O31664 (EMBL:Z99111) (259 aa) fasta scores: E(): 4.3e-25, 32.7% id in 251 aa; Orthologue of E. coli YAFV_ECOLI; Fasta hit to YAFV_ECOLI (256 aa), 82% identity in 253 aa overlap.
    
 0.913
STY3470
Argininosuccinate synthetase; Orthologue of E. coli argG (ASSY_ECOLI); Fasta hit to ASSY_ECOLI (446 aa), 96% identity in 446 aa overlap; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
     
 0.913
STY1820
Orthologue of E. coli ansA (ASG1_ECOLI); Fasta hit to ASG1_ECOLI (338 aa), 94% identity in 338 aa overlap.
   
 
 0.912
STY3259
L-asparaginase; Highly similar to Escherichia coli L-asparaginase II precursor AnsB SW:ASG2_ECOLI (P00805) (348 aa) fasta scores: E(): 0, 92.8% id in 348 aa. Contains a possible N-terminal signal sequence; Belongs to the asparaginase 1 family.
   
 
 0.912
STY0798
pnuC protein; Orthologue of E. coli pnuC (PNUC_ECOLI); Fasta hit to PNUC_ECOLI (239 aa), 89% identity in 238 aa overlap.
   
  
 0.905
STY1010
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
      
 0.905
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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