STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2839Conserved hypothetical protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. (127 aa)    
Predicted Functional Partners:
STY0968
Pyruvate formate-lyase 1 activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
   
 0.782
ybiY
Similar to Escherichia coli putative pyruvate formate-lyase 3 activating enzyme ybiY SW:PFLE_ECOLI (P75794) (308 aa) fasta scores: E(): 0, 88.0% id in 299 aa, and to Escherichia coli pyruvate formate-lyase 2 activating enzyme pflC SW:PFLC_ECOLI (P32675) (292 aa) fasta scores: E(): 6.6e-19, 35.2% id in 301 aa; Fasta hit to PFLC_ECOLI (292 aa), 35% identity in 301 aa overlap; Orthologue of E. coli PFLE_ECOLI; Fasta hit to PFLE_ECOLI (308 aa), 88% identity in 299 aa overlap.
  
   
 0.776
STY4916
Similar to Escherichia coli hypothetical 31.5 kDa protein in osmY-deoC intergenic region SW:YJJW_ECOLI () (287 aa) fasta scores: E(): 0, 80.8% id in 287 aa.
  
   
 0.774
STY0174
Pyruvate dehydrogenase complex repressor; Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd.
      
 0.687
STY1251
NADH dehydrogenase; Orthologue of E. coli ndh (DHNA_ECOLI); Fasta hit to DHNA_ECOLI (433 aa), 98% identity in 433 aa overlap.
      
 0.568
STY4104
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force (By similarity).
      
 0.502
STY2840
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
       0.432
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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