Hypothetical protein; No significant database matches.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Hypothetical protein; No significant database matches.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in p [...]

Hypothetical protein; No significant database matches.

Putative virulence determinant; Similar to Salmonella typhimurium SifA protein sifA SW:SIFA_SALTY (Q56061) (336 aa) fasta scores: E(): 0, 93.5% id in 336 aa.

Hypothetical protein; No significant database matches.

Putative pathogenicity island effector protein; Similar to Salmonella typhimurium SseF TR:O84951 (EMBL:AF020808) (260 aa) fasta scores: E(): 0, 96.5% id in 260 aa.

Hypothetical protein; No significant database matches.

Putative pathogenicity island effector protein; Similar to Salmonella typhimurium SseG TR:O84952 (EMBL:AF020808) (229 aa) fasta scores: E(): 0, 98.3% id in 229 aa.

Hypothetical protein; No significant database matches.

Secreted effector J (pseudogene); Protein sequence is in conflict with the conceptual translation; Similar to C terminus of Salmonella typhimurium LT2 secreted effector J SseJ TR:AAG02230 (EMBL:AF294582) (408 aa) fasta scores: E(): 1.7e-20, 95.7% id in 46 aa.

Hypothetical protein; No significant database matches.

Similar to Salmonella typhimurium secreted protein SspH2 TR:Q9RPH0 (EMBL:AF160727) (788 aa) fasta scores: E(): 0, 99.6% id in 788 aa and to many secreted, leucine-rich-repeat proteins e.g. Shigella flexneri 65.4 kDa antigen IpaH 4.5 SW:IPA4_SHIFL (P18009) (574 aa) fasta scores: E(): 0, 44.9% id in 515 aa.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Hypothetical protein; No significant database matches.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in p [...]

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Putative virulence determinant; Similar to Salmonella typhimurium SifA protein sifA SW:SIFA_SALTY (Q56061) (336 aa) fasta scores: E(): 0, 93.5% id in 336 aa.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Pathogenicity island 1 effector protein (function unknown); Actin-binding protein that interferes with host cell actin cytoskeleton. It stimulates actin polymerization and counteracts F- actin destabilizing proteins. Potentiates SipC activity; both are required for an efficient bacterial internalization (By similarity). Belongs to the SipA/IpaA family.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Possible secreted protein; Similar to several SopD orthologues associated with salmonella virulence: Salmonella dublin secreted protein sopD TR:O52235 (EMBL:AF030589) (317 aa) fasta scores: E(): 0, 100.0% id in 317 aa.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Putative pathogenicity island effector protein; Similar to Salmonella typhimurium SseF TR:O84951 (EMBL:AF020808) (260 aa) fasta scores: E(): 0, 96.5% id in 260 aa.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Putative pathogenicity island effector protein; Similar to Salmonella typhimurium SseG TR:O84952 (EMBL:AF020808) (229 aa) fasta scores: E(): 0, 98.3% id in 229 aa.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Secreted effector J (pseudogene); Protein sequence is in conflict with the conceptual translation; Similar to C terminus of Salmonella typhimurium LT2 secreted effector J SseJ TR:AAG02230 (EMBL:AF294582) (408 aa) fasta scores: E(): 1.7e-20, 95.7% id in 46 aa.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Similar to Salmonella typhimurium secreted protein SspH2 TR:Q9RPH0 (EMBL:AF160727) (788 aa) fasta scores: E(): 0, 99.6% id in 788 aa and to many secreted, leucine-rich-repeat proteins e.g. Shigella flexneri 65.4 kDa antigen IpaH 4.5 SW:IPA4_SHIFL (P18009) (574 aa) fasta scores: E(): 0, 44.9% id in 515 aa.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Tyrosine phosphatase (associated with virulence); Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear (By similarity).

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in p [...]

Hypothetical protein; No significant database matches.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in p [...]

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity); Belongs to the peptidase C79 family.

Conserved hypothetical protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in p [...]

Putative virulence determinant; Similar to Salmonella typhimurium SifA protein sifA SW:SIFA_SALTY (Q56061) (336 aa) fasta scores: E(): 0, 93.5% id in 336 aa.