STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqcBPutative RNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family. (260 aa)    
Predicted Functional Partners:
yqcC
Similar to Escherichia coli hypothetical 12.8 kDa protein in barA-syd intergenic region YqcC SW:YQCC_ECOLI (Q46919) (109 aa) fasta scores: E(): 0, 80.7% id in 109 aa, and to Haemophilus influenzae hypothetical protein HI1436 SW:YQCC_HAEIN (Q57152) (106 aa) fasta scores: E(): 9.7e-11, 36.4% id in 99 aa.
  
  
 0.921
STY0132
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
      
 0.812
STY2725
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Orthologue of E. coli purC (PUR7_ECOLI); Fasta hit to PUR7_ECOLI (237 aa), 95% identity in 237 aa overlap; Belongs to the SAICAR synthetase family.
   
  
 0.812
STY3102
Similar to Escherichia coli hypothetical protein TR:Q46917 (EMBL:U29581) (149 aa) fasta scores: E(): 0, 88.6% id in 149 aa and to Erwinia carotovora TR:Q47418 (EMBL:X79474) (151 aa) fasta scores: E(): 0, 64.9% id in 148 aa; Orthologue of E. coli Q46917; Fasta hit to Q46917 (149 aa), 89% identity in 149 aa overlap.
  
    0.750
rplQ
50S ribosomal subunit protein L17; Orthologue of E. coli rplQ (RL17_ECOLI); Fasta hit to RL17_ECOLI (127 aa), 99% identity in 127 aa overlap.
 
 
   0.618
rplC
50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
 
 
 0.595
STY3525
50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
   0.589
STY3053
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
    
 
 0.576
STY3937
Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
 
 0.567
STY0693
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.565
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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