STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltCMembrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (361 aa)    
Predicted Functional Partners:
STY2813
Putative exported protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.
 
   
 0.834
STY2952
Membrane-bound lytic transglycosylase B precursor; Orthologue of E. coli mltB (MLTB_ECOLI); Fasta hit to MLTB_ECOLI (361 aa), 92% identity in 361 aa overlap.
      
 0.722
STY3128
Membrane-bound lytic murein transglycosylase A precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
      
 0.713
slt
Similar to Escherichia coli soluble lytic murein transglycosylase precursor slt or sltY SW:SLT_ECOLI (P03810; P76820) (645 aa) fasta scores: E(): 0, 91.2% id in 627 aa.
  
   
 0.674
STY3266
Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.
  
  
 0.595
STY0995
KicA protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.545
STY3265
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
  
    0.510
STY0994
Killing factor KicB; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.505
STY3268
Nucleoside permease; Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force; Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family.
       0.480
STY0689
Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family.
     
 0.473
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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