STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3306D-mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (394 aa)    
Predicted Functional Partners:
STY3307
D-mannonate oxidoreductase; Fasta hit to YEIQ_ECOLI (488 aa), 57% identity in 470 aa overlap; Fasta hit to YDFI_ECOLI (486 aa), 57% identity in 485 aa overlap; Orthologue of E. coli uxuB (UXUB_ECOLI); Fasta hit to UXUB_ECOLI (486 aa), 80% identity in 484 aa overlap; Belongs to the mannitol dehydrogenase family.
 
 
 0.995
STY3308
Uronate isomerase (glucuronate isomerase); Orthologue of E. coli uxaC (UXAC_ECOLI); Fasta hit to UXAC_ECOLI (470 aa), 67% identity in 470 aa overlap.
 
  
 0.995
STY1553
Similar to Escherichia coli D-mannonate oxidoreductase uxuB SW:UXUB_ECOLI (P39160) (486 aa) fasta scores: E(): 0, 59.3% id in 472 aa; Fasta hit to UXUB_ECOLI (486 aa), 59% identity in 472 aa overlap; Fasta hit to YEIQ_ECOLI (488 aa), 57% identity in 468 aa overlap; Orthologue of E. coli YDFI_ECOLI; Fasta hit to YDFI_ECOLI (486 aa), 81% identity in 484 aa overlap; Belongs to the mannitol dehydrogenase family.
 
 
 0.963
STY3162
2-keto-3-deoxygluconate oxidoreductase; Orthologue of E. coli kduD (KDUD_ECOLI); Fasta hit to KDUD_ECOLI (253 aa), 93% identity in 253 aa overlap; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.948
STY1556
Starvation sensing protein RspA; Orthologue of E. coli rspA (RSPA_ECOLI); Fasta hit to RSPA_ECOLI (404 aa), 95% identity in 404 aa overlap.
    
 0.907
STY4191
2-dehydro-3-deoxygluconokinase; Orthologue of E. coli kdgK (KDGK_ECOLI); Fasta hit to KDGK_ECOLI (309 aa), 92% identity in 308 aa overlap.
 
  
 0.904
STY3163
5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
  
 0.857
STY3305
Similar to Escherichia coli hexuronate transporter ExuT SW:EXUT_ECOLI (P42609) (472 aa) fasta scores: E(): 0, 46.7% id in 435 aa and to Erwinia chrysanthemi ExuT protein TR:P94774 (EMBL:U86689) (345 aa) fasta scores: E(): 0, 46.2% id in 333 aa.
 
  
 0.852
STY2290
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.800
STY3219
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
  0.800
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.