STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3376Glycogen synthesis protein GlgS; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. (67 aa)    
Predicted Functional Partners:
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
      
 0.649
STY2171
Similar to Salmonella typhimurium cytoplasmic alpha-amylase amyA SW:AMY2_SALTY (P26613) (494 aa) fasta scores: E(): 0, 98.4% id in 494 aa; Orthologue of E. coli amyA (AMY2_ECOLI); Fasta hit to AMY2_ECOLI (495 aa), 89% identity in 494 aa overlap.
      
 0.562
STY4282
Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
      
 0.543
glgX
Glycogen operon protein; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
      
 0.510
STY1908
Putative membrane protein; Similar to Escherichia coli hypothetical 10.5 kDa protein in pth-prs intergenic region ychH SW:YCHH_ECOLI (P31807) (92 aa) fasta scores: E(): 3.6e-26, 90.4% id in 73 aa.
   
    0.446
STY3377
Putative membrane protein; Orthologue of E. coli P76657; Fasta hit to P76657 (209 aa), 72% identity in 201 aa overlap. Contains multiple possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence.
       0.441
STY3378
Putative exported protein; Orthologue of E. coli YQIK_ECOLI; Fasta hit to YQIK_ECOLI (553 aa), 93% identity in 549 aa overlap. Contains a possible N-terminal signal sequence and a possible coiled-coil region between residues 345..446.
       0.414
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
      
 0.401
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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