STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
STY3516Possible kinase; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (291 aa)    
Predicted Functional Partners:
STY1166
Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 0.997
STY3520
N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
 
 
 0.993
STY3515
Conserved hypothetical protein; Fasta hit to YJGK_ECOLI (150 aa), 32% identity in 148 aa overlap; Orthologue of E. coli YHCH_ECOLI; Fasta hit to YHCH_ECOLI (154 aa), 81% identity in 154 aa overlap.
  
  
 0.975
STY3519
Putative sialic acid transporter; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
 
  
 0.884
STY0722
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 
   
 0.857
STY0723
Pts system, N-acetylglucosamine-specific IIABC component; Orthologue of E. coli nagE (PTAA_ECOLI); Fasta hit to PTAA_ECOLI (648 aa), 93% identity in 648 aa overlap.
  
 
 0.832
STY3077
Highly similar to Escherichia coli putative 6-pyruvoyl tetrahydrobiopterin synthase YgcM SW:PTPS_ECOLI (Q46903) (121 aa) fasta scores: E(): 0, 94.2% id in 120 aa; Orthologue of E. coli PTPS_ECOLI; Fasta hit to PTPS_ECOLI (121 aa), 94% identity in 120 aa overlap.
      
 0.812
STY1242
PTS system, glucose-specific IIBC component; Fasta hit to PTOA_ECOLI (530 aa), 37% identity in 513 aa overlap; Orthologue of E. coli ptsG (PTGB_ECOLI); Fasta hit to PTGB_ECOLI (477 aa), 97% identity in 476 aa overlap.
  
 
 0.743
STY2816
Putative PTS system IIBC component; Similar to Bacillus subtilis negative regulatory protein of SacY sacX or sacS SW:SACX_BACSU (P15400) (459 aa) fasta scores: E(): 0, 33.1% id in 472 aa and putative PTS components e.g. Bacillus halodurans putative PTS system, sucrose phosphotransferase enzyme II BC component BH3574 TR:Q9K700 (EMBL:AP001519) (453 aa) fasta scores: E(): 0, 47.4% id in 454 aa; Orthologue of E. coli P77272; Fasta hit to P77272 (474 aa), 39% identity in 470 aa overlap.
  
 
 0.743
treB
Similar to Escherichia coli pts system, trehalose-specific IIBC component treB SW:PTTB_ECOLI (P36672) (473 aa) fasta scores: E(): 0, 89.0% id in 472 aa and to Bacillus subtilis probable pts system, trehalose-specific IIBC component TreP treP or treB SW:PTTB_BACSU (P39794) (470 aa) fasta scores: E(): 0, 41.0% id in 463 aa.
  
 
 0.743
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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