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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3565Fis DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. (98 aa)    
Predicted Functional Partners:
STY3564
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
  
  
 0.958
crp
Cyclic AMP receptor protein,catabolite gene activator; Similar to Salmonella typhimurium, and Klebsiella aerogenes catabolite gene activator crp or cap SW:CRP_SALTY (P06170) (210 aa) fasta scores: E(): 0, 99.5% id in 210 aa, and to Escherichia coli, and Shigella flexneri catabolite gene activator crp or cap or csm SW:CRP_ECOLI (P03020) (210 aa) fasta scores: E(): 0, 99.0% id in 210 aa.
      
 0.848
STY0516
Haemolysin expression modulating protein; Fasta hit to YDGT_ECOLI (71 aa), 38% identity in 71 aa overlap; Orthologue of E. coli hha (HHA_ECOLI); Fasta hit to HHA_ECOLI (72 aa), 99% identity in 72 aa overlap.
      
 0.652
STY2404
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.
  
  
 0.603
STY4439
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
  
  
 0.603
STY3871
GTP-binding protein; Similar to Escherichia coli GTP-binding protein implicated in virulence in EPEC strains, TypA SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 0, 97.0% id in 591 aa.
   
  
 0.590
STY0052
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
    0.546
STY3566
Putative adenine-specific DNA-modification methylase; Orthologue of E. coli yhdJ (YHDJ_ECOLI); Fasta hit to YHDJ_ECOLI (294 aa), 80% identity in 283 aa overlap; Belongs to the N(4)/N(6)-methyltransferase family.
       0.545
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
  
  
 0.527
STY3568
Putative exported protein; Similar in parts to several e.g. Synechocystis sp nitrogen fixation positive activator protein nifL TR:P72843 (EMBL:D90901) (840 aa) fasta scores: E(): 0, 44.1% id in 279 aa. Contains multiple possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence. Contains C-terminal deletion relative to S. typhimurium.
   
 
 0.519
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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