STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3596Putative membrane protein; Uptake of biotin; Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family. (299 aa)    
Predicted Functional Partners:
yigL
Conserved hypothetical protein; Similar to Salmonella typhimurium LT2 YigL protein yigL TR:AAF33430 (EMBL:UNNKOWN ACCESSION) (266 aa) fasta scores: E(): 0, 100.0% id in 266 aa, and to Escherichia coli hypothetical 29.8 kDa protein in pldb-metr intergenic region. hypothetical 29.8 kda protein in pldb-metr intergenic region SW:YIGL_ECOLI (P27848) (265 aa) fasta scores: E(): 0, 84.5% id in 265 aa; Fasta hit to COF_ECOLI (272 aa), 39% identity in 260 aa overlap; Orthologue of E. coli yigL (YIGL_ECOLI); Fasta hit to YIGL_ECOLI (265 aa), 85% identity in 265 aa overlap.
     
 0.784
STY3598
Lysophospholipase L2; Orthologue of E. coli pldB (PLDB_ECOLI); Fasta hit to PLDB_ECOLI (340 aa), 82% identity in 336 aa overlap.
     
 0.690
STY3382
Putative membrane protein; Orthologue of E. coli ygiM (YGIM_ECOLI); Fasta hit to YGIM_ECOLI (206 aa), 91% identity in 206 aa overlap. Contains a possible membrane spanning hydrophobic domain.
  
   
 0.672
STY1891
Similar to Bordetella pertussis pertussis toxin subunit 2 precursor ptxB SW:TOX2_BORPE (P04978) (226 aa) fasta scores: E(): 0.0089, 30.7% id in 101 aa, and to Bordetella pertussis pertussis toxin subunit 3 precursor ptxC SW:TOX3_BORPE (P04979) (227 aa) fasta scores: E(): 0.14, 29.6% id in 108 aa.
      
 0.670
STY3562
Sodium/pantothenate symporter (pantothenate permease); Orthologue of E. coli panF (PANF_ECOLI); Fasta hit to PANF_ECOLI (483 aa), 94% identity in 483 aa overlap; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.642
cdtB
Putative toxin-like protein; Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement.
     
 0.564
ytfN
Putative exported protein; Similar to Escherichia coli hypothetical 136.8 kDa protein in msra-chpb intergenic region ytfN SW:YTFN_ECOLI (P39321) (1259 aa) fasta scores: E(): 0, 86.3% id in 1259 aa, and to Haemophilus influenzae hypothetical protein Hi0696 hi0696 SW:YTFN_HAEIN (Q57523) (1298 aa) fasta scores: E(): 0, 33.1% id in 1294 aa. Contains a possible N-terminal signal sequence.
  
     0.508
rhtB
Homoserine/homoserine lactone efflux protein; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family.
       0.473
STY0934
Putative membrane protein; Orthologue of E. coli YBJE_ECOLI; Fasta hit to YBJE_ECOLI (315 aa), 89% identity in 299 aa overlap.
  
     0.425
STY3120
Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
 
     0.405
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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