STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yifLPutative lipoprotein; Similar to Escherichia coli hypothetical 7.2 kDa protein in cyay-dapf intergenic region yifL SW:YIFL_ECOLI (P39166) (67 aa) fasta scores: E(): 1.8e-22, 91.0% id in 67 aa. ontains a possible N-terminal signal sequence. (67 aa)    
Predicted Functional Partners:
STY3612
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
  
 0.709
STY3610
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the t [...]
     
 0.704
STY3611
Conserved hypothetical protein; Orthologue of E. coli yigA (YIGA_ECOLI); Fasta hit to YIGA_ECOLI (235 aa), 86% identity in 235 aa overlap.
       0.686
STY3609
Conserved hypothetical protein; Orthologue of E. coli yigB (YIGB_ECOLI); Fasta hit to YIGB_ECOLI (238 aa), 87% identity in 238 aa overlap.
       0.671
STY3616
CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
       0.567
STY3614
Possible exported protein; Contains a possible N-terminal signal sequence.
       0.503
STY2287
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; Similar to Salmonella typhimurium histidine biosynthesis bifunctional protein HisI [includes: phosphoribosyl-AMP cyclohydrolase hisI SW:HIS2_SALTY (P10367) (203 aa) fasta scores: E(): 0, 97.5% id in 203 aa; Orthologue of E. coli hisI (HIS2_ECOLI); Fasta hit to HIS2_ECOLI (203 aa), 91% identity in 203 aa overlap; In the C-terminal section; belongs to the PRA-PH family.
   
    0.499
STY3615
Putative membrane protein; Contains possible membrane spanning hydrophobic domains.
       0.482
stcB
Similar to many e.g. Klebsiella pneumoniae chaperone protein MrkB precursor mrkB SW:MRKB_KLEPN (P21646) (233 aa) fasta scores: E(): 6.1e-26, 35.7% id in 235 aa and Bordetella pertussis chaperone protein precursor fimB or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 8.7e-23, 33.8% id in 231 aa; Fasta hit to YRAI_ECOLI (231 aa), 30% identity in 220 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 33% identity in 216 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 35% identity in 222 aa overlap; Orthologue of E. coli yehC (YEHC_ECOLI); Fasta hit to YEHC_ECOLI (239 aa), 64% identity [...]
      
 0.463
yjeT
Putative membrane protein; Similar to Escherichia coli hypothetical 7.2 kDa protein in hflc-pura intergenic region yjeT SW:YJET_ECOLI (P39289) (65 aa) fasta scores: E(): 4.1e-22, 89.2% id in 65 aa Contains possible membrane spanning hydrophobic domains.
      
 0.463
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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