STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3713Possible exported protein; Binds zinc. Could be an important component of the zinc- balancing mechanism (By similarity); Belongs to the ZraP family. (151 aa)    
Predicted Functional Partners:
STY3712
Two-component system sensor protein; Member of the two-component regulatory system ZraS/ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium (By similarity).
 
   
 0.928
STY3711
Transcriptional regulatory protein; Member of the two-component regulatory system ZraS/ZraR. When activated by ZraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon (By similarity).
 
   
 0.899
STY2385
Putative lipoprotein; Similar to Listeria monocytogenes hypothetical lipoprotein SW:YORZ_LISMO (P33385) (153 aa) fasta scores: E(): 3.7e-21, 42.7% id in 150 aa. Contains probable N-terminal signal sequence; Orthologue of E. coli yehR (YEHR_ECOLI); Fasta hit to YEHR_ECOLI (153 aa), 73% identity in 153 aa overlap.
  
     0.709
STY0196
Putative PTS system IIA component; Similar to Vibrio furnissii PTS permease for mannose subunit IIIman N terminal domain manW TR:P96165 (EMBL:U65015) (146 aa) fasta scores: E(): 1.3e-10, 30.7% id in 137 aa, and to Klebsiella pneumoniae PTS system, sorbose-specific IIA component sorF SW:PTRA_KLEPN (P37080) (135 aa) fasta scores: E(): 0.0053, 23.5% id in 132 aa; Orthologue of E. coli yadI (YADI_ECOLI); Fasta hit to YADI_ECOLI (146 aa), 77% identity in 146 aa overlap.
  
     0.646
STY1248
Conserved hypothetical protein; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
  
     0.636
STY1545
Putative periplasmic protein; Orthologue of E. coli ydeI (YDEI_ECOLI); Fasta hit to YDEI_ECOLI (130 aa), 80% identity in 107 aa overlap.
  
     0.600
STY2386
Putative lipoprotein; Similar to Listeria monocytogenes hypothetical lipoprotein SW:YORZ_LISMO (P33385) (153 aa) fasta scores: E(): 7.6e-16, 38.3% id in 133 aa and Escherichia coli hypothetical lipoprotein SW:YEHR_ECOLI (P33354) (153 aa) fasta scores: E(): 1.3e-11, 30.9% id in 139 aa. Contains probable N-terminal signal sequence.
  
     0.599
STY2645
Putative membrane protein; Orthologue of E. coli P76526; Fasta hit to P76526 (418 aa), 80% identity in 408 aa overlap. Contains hydrophobic, probable membrane-spanning regions.
  
     0.596
STY2514
Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor; Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
  
     0.593
STY1490
Putative regulatory protein; Similar to Streptomyces coelicolor putative transcriptional regulator sc6a5.24C TR:Q9X7X0 (EMBL:AL049485) (206 aa) fasta scores: E(): 1.1e-07, 32.9% id in 173 aa.
  
     0.579
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.