STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
STY3758Putative transaldolase; Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction; Belongs to the transaldolase family. Type 3A subfamily. (220 aa)    
Predicted Functional Partners:
STY3759
Glycerol dehydrogenase; Fasta hit to YBDH_ECOLI (362 aa), 30% identity in 356 aa overlap; Orthologue of E. coli gldA (GLDA_ECOLI); Fasta hit to GLDA_ECOLI (367 aa), 92% identity in 367 aa overlap.
 
    0.897
STY2460
Putative helicase; Orthologue of E. coli yejH (YEJH_ECOLI); Fasta hit to YEJH_ECOLI (586 aa), 95% identity in 586 aa overlap.
    
 
 0.820
STY2711
Transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.802
STY3236
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.802
STY2571
Similar to the N-terminal halves of transketolases e.g. Mus musculus transketolase tkt SW:TKT_MOUSE (P40142) (623 aa) fasta scores: E(): 5.6e-24, 33.0% id in 267 aa.
 
  
 0.685
STY1419
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap.
  
  
 0.675
STY2570
Similar to the C-terminal halves of transketolases e.g. Mus musculus transketolase tkt SW:TKT_MOUSE (P40142) (623 aa) fasta scores: E(): 4e-27, 33.1% id in 311 aa and Escherichia coli 1-deoxyxylulose-5-phosphate synthase dxs SW:DXS_ECOLI (P77488) (619 aa) fasta scores: E(): 4e-19, 27.6% id in 308 aa.
 
 
 0.647
STY2290
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 
 0.626
maeB
NADP-dependent malate dehydrogenase (decarboxylating); Similar to Escherichia coli NADP-dependent malic enzyme maeB SW:MAO2_ECOLI (P76558) (759 aa) fasta scores: E(): 0, 94.3% id in 759 aa; Orthologue of E. coli MAO2_ECOLI; Fasta hit to MAO2_ECOLI (759 aa), 94% identity in 759 aa overlap.
  
  
 0.618
yacK
Possible multicopper oxidase precursor; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm (By similarity).
      
 0.593
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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