STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
STY3886Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (194 aa)    
Predicted Functional Partners:
STY3887
Molybdopterin-guanine dinucleotide biosynthesis protein B; Orthologue of E. coli MOBB_ECOLI; Fasta hit to MOBB_ECOLI (174 aa), 78% identity in 167 aa overlap.
 
 0.998
STY0885
Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.991
STY1419
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap.
  
  
 0.925
STY0838
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
   
 0.857
STY0837
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
 
  
 0.692
STY4484
Similar to Escherichia coli formate dehydrogenase H FdhF SW:FDHF_ECOLI (P07658) (715 aa) fasta scores: E(): 0, 97.5% id in 714 aa, and to Methanobacterium thermoformicicum formate dehydrogenase, alpha subunit FdhA TR:Q50569 (EMBL:U52681) (681 aa) fasta scores: E(): 0, 41.9% id in 688 aa. The CDS contains an opal UGA stop codon at position 140. In E. coli the nonsense mutation is supressed by the addition of the non standard amino acid, selenocysteine. Upstream of the opal codon there is a 20 bp stem loop structure; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.663
STY0812
Putative molybdenum transport protein ModE; Orthologue of E. coli modE (MODE_ECOLI); Fasta hit to MODE_ECOLI (262 aa), 89% identity in 262 aa overlap.
 
   
 0.648
STY0836
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.630
STY3885
Conserved hypothetical protein; Orthologue of E. coli yihD (YIHD_ECOLI); Fasta hit to YIHD_ECOLI (89 aa), 94% identity in 89 aa overlap.
 
     0.621
STY0840
Molybdopterin converting factor, subunit 2; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family.
 
  
 0.578
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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