STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3901Asparagine synthetase A; Orthologue of E. coli asnA (ASNA_ECOLI); Fasta hit to ASNA_ECOLI (330 aa), 95% identity in 330 aa overlap; Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily. (330 aa)    
Predicted Functional Partners:
STY0718
Asparagine synthetase B; Orthologue of E. coli asnB (ASNB_ECOLI); Fasta hit to ASNB_ECOLI (553 aa), 95% identity in 553 aa overlap.
   
 
 0.918
STY1820
Orthologue of E. coli ansA (ASG1_ECOLI); Fasta hit to ASG1_ECOLI (338 aa), 94% identity in 338 aa overlap.
     
 0.910
STY3470
Argininosuccinate synthetase; Orthologue of E. coli argG (ASSY_ECOLI); Fasta hit to ASSY_ECOLI (446 aa), 96% identity in 446 aa overlap; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
   
 
  0.903
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.901
pyrB
Similar to Salmonella typhimurium aspartate carbamoyltransferase catalytic chain PyrB SW:PYRB_SALTY (P08420) (309 aa) fasta scores: E(): 0, 98.4% id in 310 aa, and to Escherichia coli aspartate carbamoyltransferase catalytic chain PyrB SW:PYRB_ECOLI (P00479) (310 aa) fasta scores: E(): 0, 95.2% id in 310 aa; Fasta hit to OTC2_ECOLI (333 aa), 32% identity in 298 aa overlap; Fasta hit to OTC1_ECOLI (333 aa), 32% identity in 295 aa overlap.
     
 0.901
STY0886
Similar to Escherichia coli putative L-asparaginase precursor ybiK SW:ASGX_ECOLI (P37595; P75795) (321 aa) fasta scores: E(): 0, 88.2% id in 313 aa, and to Arabidopsis thaliana L-asparaginase SW:ASPG_ARATH (P50287) (315 aa) fasta scores: E(): 0, 44.8% id in 299 aa, and to Lupinus luteus L-asparaginase SW:ASPG_LUPLU (Q9ZSD6) (325 aa) fasta scores: E(): 6.5e-16, 45.5% id in 308 aa; Orthologue of E. coli ybiK (ASGX_ECOLI); Fasta hit to ASGX_ECOLI (321 aa), 88% identity in 313 aa overlap.
     
  0.900
STY1000
Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
STY2834
L-aspartate oxidase (quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
  0.900
STY3259
L-asparaginase; Highly similar to Escherichia coli L-asparaginase II precursor AnsB SW:ASG2_ECOLI (P00805) (348 aa) fasta scores: E(): 0, 92.8% id in 348 aa. Contains a possible N-terminal signal sequence; Belongs to the asparaginase 1 family.
     
  0.900
aspA
Similar to Escherichia coli Aspartate ammonia-lyase aspA SW:ASPA_ECOLI (P04422) (478 aa) fasta scores: E(): 0, 97.1% id in 478 aa, and to Serratia marcescens Aspartate ammonia-lyase aspA SW:ASPA_SERMA (P33109) (478 aa) fasta scores: E(): 0, 89.7% id in 478 aa.
     
  0.900
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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