STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY4210Conserved hypothetical protein; Specifically methylates the guanosine in position 1516 of 16S rRNA. (252 aa)    
Predicted Functional Partners:
STY4209
Similar to Salmonella typhimurium oligopeptidase A PrlC SW:OPDA_SALTY (P27237) (680 aa) fasta scores: E(): 0, 99.7% id in 680 aa, and to Escherichia coli oligopeptidase A PrlC or opdA SW:OPDA_ECOLI (P27298) (680 aa) fasta scores: E(): 0, 95.1% id in 680 aa.
  
  
 0.974
yafE
Putative methyltransferase; Similar to Escherichia coli hypothetical 23.0 kDa protein in aspu-mltd intergenic region yafE SW:YAFE_ECOLI (P30866) (207 aa) fasta scores: E(): 0, 71.1% id in 204 aa, and to Lactococcus lactis probable menaquinone biosynthesis methyltransferase SW:GRCB_LACLA (P49016) (252 aa) fasta scores: E(): 6.3e-13, 28.4% id in 190 aa, and to Micrococcus luteus 2-hexaprenyl-1,4-naphthoquinone methyltransferase menG TR:O66128 (EMBL:AB003188) (246 aa) fasta scores: E(): 6e-10, 28.6% id in 185 aa.
   
  
 0.856
STY0283
Conserved hypothetical protein; Orthologue of E. coli YAFS_ECOLI; Fasta hit to YAFS_ECOLI (240 aa), 87% identity in 238 aa overlap.
 
  
 0.843
STY3885
Conserved hypothetical protein; Orthologue of E. coli yihD (YIHD_ECOLI); Fasta hit to YIHD_ECOLI (89 aa), 94% identity in 89 aa overlap.
 
   
 0.833
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
  
 0.568
STY3939
RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
    0.499
STY3707
Conserved hypothetical protein; Orthologue of E. coli yifE (YIFE_ECOLI); Fasta hit to YIFE_ECOLI (111 aa), 96% identity in 111 aa overlap; Belongs to the UPF0438 family.
      
 0.468
STY4208
Putative lipoprotein; Similar to Escherichia coli hypothetical 24.8 kDa protein in ibpA-gyrB intergenic region YidX SW:YIDX_ECOLI (P31461) (223 aa) fasta scores: E(): 6e-27, 45.1% id in 175 aa. Putative N-terminal lipoprotein attachment site.
       0.466
smtA
SmtA protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
  
   
 0.436
STY3447
Possible exported protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
  
     0.432
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.