STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kefBGlutathione-regulated potassium-efflux system protein (K(+)/H(+)antiporter); Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa)    
Predicted Functional Partners:
yheR
Putative oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
 
 
 0.987
STY0100
Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
 
 
 0.915
yheV
Similar to Escherichia coli hypothetical 7.6 kDa protein in slyd-kefb intergenic region yheV SW:YHEV_ECOLI (P56622) (66 aa) fasta scores: E(): 1.7e-27, 90.9% id in 66 aa.
       0.832
STY3474
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
     
 0.762
STY0536
Putative transport protein; Fasta hit to KEFB_ECOLI (601 aa), 31% identity in 526 aa overlap; Orthologue of E. coli ybaL (YBAL_ECOLI); Fasta hit to YBAL_ECOLI (558 aa), 95% identity in 556 aa overlap; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
0.706
STY4422
Putative membrane protein; Similar to Salmonella typhimurium host expressed protein, Mig-7 TR:O30901 (EMBL:AF020807) (136 aa) fasta scores: E(): 0, 100.0% id in 136 aa, and to Escherichia coli hypothetical 15.6 kDa protein in pgi-xylE intergenic region YjbA SW:YJBA_ECOLI (P23896) (136 aa) fasta scores: E(): 0, 87.5% id in 136 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein.
      
 0.699
STY1218
Flagellar basal-body rod protein FlgG (distal rod protein); Fasta hit to FLGF_ECOLI (251 aa), 32% identity in 261 aa overlap; Orthologue of E. coli flgG (FLGG_ECOLI); Fasta hit to FLGG_ECOLI (260 aa), 99% identity in 260 aa overlap; Belongs to the flagella basal body rod proteins family.
    
   0.659
STY1975
Heat shock protein; Orthologue of E. coli htpX (HTPX_ECOLI); Fasta hit to HTPX_ECOLI (293 aa), 96% identity in 293 aa overlap; Belongs to the peptidase M48B family.
  
  
 0.653
STY0544
Copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity).
  
  
 0.627
STY1312
Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
      
 0.624
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.