STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yheMConserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (118 aa)    
Predicted Functional Partners:
yheN
Conserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
 
 0.999
yheL
Conserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
 
 0.999
STY1111
Hypothetical protein in helD-serT intergenic region; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD (By similarity).
 
  
 0.910
STY1283
Conserved hypothetical protein; Similar to Klebsiella pneumoniae YchN protein ychN TR:Q9RLW1 (EMBL:L27824) (117 aa) fasta scores: E(): 0, 92.3% id in 117 aa; Orthologue of E. coli ychN (YCHN_ECOLI); Fasta hit to YCHN_ECOLI (117 aa), 92% identity in 117 aa overlap.
  
 
 0.835
yheO
Similar to Escherichia coli hypothetical 26.8 kDa protein in rpsl-fkpa intergenic region yheO SW:YHEO_ECOLI (P45533) (240 aa) fasta scores: E(): 0, 97.9% id in 240 aa, and to Haemophilus influenzae hypothetical protein Hi0575 hi0575 SW:YHEO_HAEIN (P44761) (221 aa) fasta scores: E(): 0, 67.6% id in 219 aa; Orthologue of E. coli YHEO_ECOLI; Fasta hit to YHEO_ECOLI (240 aa), 98% identity in 240 aa overlap.
  
    0.805
STY3588
Conserved hypothetical protein; Orthologue of E. coli yigP (YIGP_ECOLI); Fasta hit to YIGP_ECOLI (201 aa), 87% identity in 201 aa overlap.
  
   
 0.717
STY0687
Conserved hypothetical protein; Orthologue of E. coli ybeD (YBED_ECOLI); Fasta hit to YBED_ECOLI (87 aa), 98% identity in 87 aa overlap; Belongs to the UPF0250 family.
  
   
 0.698
yhhP
Conserved hypothetical protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
 
   
 0.668
STY0715
PhoH-like ATP-binding protein; Orthologue of E. coli PHOL_ECOLI; Fasta hit to PHOL_ECOLI (359 aa), 96% identity in 359 aa overlap.
   
  
 0.647
STY0714
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
      
 0.641
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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