node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0002 | STY1956 | gene:17584057 | gene:17585874 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.822 |
STY0002 | STY2430 | gene:17584057 | gene:17586333 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Putative L-serine dehydratase; Fasta hit to SDHM_ECOLI (455 aa), 50% identity in 452 aa overlap; Fasta hit to TDCG_ECOLI (454 aa), 51% identity in 450 aa overlap; Paralogue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 49% identity in 453 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.822 |
STY0002 | STY3427 | gene:17584057 | gene:17587278 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Catabolic threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.681 |
STY0002 | STY3652 | gene:17584057 | gene:17587507 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.681 |
STY0002 | STY3761 | gene:17584057 | gene:17587627 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 5,10 methylenetetrahydrofolate reductase; Orthologue of E. coli metF (METF_ECOLI); Fasta hit to METF_ECOLI (296 aa), 96% identity in 296 aa overlap; Belongs to the methylenetetrahydrofolate reductase family. | 0.827 |
STY0002 | STY3768 | gene:17584057 | gene:17587633 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Bifunctional aspartokinase II/homoserine dehydrogenase IIcan I write; Fasta hit to AK1H_ECOLI (820 aa), 30% identity in 823 aa overlap; Orthologue of E. coli metL (AK2H_ECOLI); Fasta hit to AK2H_ECOLI (809 aa), 94% identity in 809 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.987 |
STY0002 | STY3769 | gene:17584057 | gene:17587634 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Cystathionine gamma-synthase; Fasta hit to METC_ECOLI (395 aa), 31% identity in 394 aa overlap; Orthologue of E. coli metB (METB_ECOLI); Fasta hit to METB_ECOLI (386 aa), 96% identity in 386 aa overlap. | 0.941 |
STY0002 | STY4405 | gene:17584057 | gene:17588237 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.990 |
STY0002 | metA | gene:17584057 | gene:17588232 | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.971 |
STY1325 | STY1956 | gene:17585286 | gene:17585874 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
STY1325 | STY2430 | gene:17585286 | gene:17586333 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Putative L-serine dehydratase; Fasta hit to SDHM_ECOLI (455 aa), 50% identity in 452 aa overlap; Fasta hit to TDCG_ECOLI (454 aa), 51% identity in 450 aa overlap; Paralogue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 49% identity in 453 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
STY1325 | STY3427 | gene:17585286 | gene:17587278 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Catabolic threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.926 |
STY1325 | STY3652 | gene:17585286 | gene:17587507 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.926 |
STY1325 | metA | gene:17585286 | gene:17588232 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.813 |
STY1956 | STY0002 | gene:17585874 | gene:17584057 | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.822 |
STY1956 | STY1325 | gene:17585874 | gene:17585286 | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
STY1956 | STY2430 | gene:17585874 | gene:17586333 | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative L-serine dehydratase; Fasta hit to SDHM_ECOLI (455 aa), 50% identity in 452 aa overlap; Fasta hit to TDCG_ECOLI (454 aa), 51% identity in 450 aa overlap; Paralogue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 49% identity in 453 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.905 |
STY1956 | STY3427 | gene:17585874 | gene:17587278 | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Catabolic threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.910 |
STY1956 | STY3652 | gene:17585874 | gene:17587507 | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.911 |
STY1956 | STY3768 | gene:17585874 | gene:17587633 | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Bifunctional aspartokinase II/homoserine dehydrogenase IIcan I write; Fasta hit to AK1H_ECOLI (820 aa), 30% identity in 823 aa overlap; Orthologue of E. coli metL (AK2H_ECOLI); Fasta hit to AK2H_ECOLI (809 aa), 94% identity in 809 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.822 |