STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY4431Similar to Escherichia coli glycerol-3-phosphate acyltransferase PlsB SW:PLSB_ECOLI (P00482) (806 aa) fasta scores: E(): 0, 94.9% id in 805 aa, and to Haemophilus influenzae glycerol-3-phosphate acyltransferase PlsB SW:PLSB_HAEIN (P44857) (810 aa) fasta scores: E(): 0, 56.6% id in 806 aa; Belongs to the GPAT/DAPAT family. (806 aa)    
Predicted Functional Partners:
STY3350
1-acyl-glycerol-3-phosphate acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-acyl-carrier-protein as the fatty acyl donor (By similarity).
 
 
 0.994
STY1231
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
     
 0.979
STY3386
Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl- PO(4); Belongs to the PlsY family.
     
 0.979
gpsA
Similar to Escherichia coli glycerol-3-phosphate dehydrogenase [NAD+] gpsA SW:GPDA_ECOLI (P37606) (339 aa) fasta scores: E(): 0, 95.0% id in 339 aa, and to Bacillus subtilis glycerol-3-phosphate dehydrogenase [NAD gpsA or glyC SW:GPDA_BACSU (P46919) (345 aa) fasta scores: E(): 0, 38.4% id in 331 aa; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
    
 0.921
STY2513
Anaerobic glycerol-3-phosphate dehydrogenase subunit A; Orthologue of E. coli glpA (GLPA_ECOLI); Fasta hit to GLPA_ECOLI (542 aa), 93% identity in 542 aa overlap; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
    
 0.912
glpD
Similar to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 0, 90.6% id in 502 aa, and to Pseudomonas tolaasii glycerol-3-phosphate dehydrogenase GlpD SW:GLPD_PSETO (O83004) (513 aa) fasta scores: E(): 0, 59.9% id in 491 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
    
 0.912
STY3784
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
     
 0.910
STY2514
Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor; Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
     
  0.900
STY2515
Anaerobic glycerol-3-phosphate dehydrogenase subunit C; Orthologue of E. coli glpC (GLPC_ECOLI); Fasta hit to GLPC_ECOLI (396 aa), 94% identity in 395 aa overlap.
     
  0.900
STY3747
Possible TetR-family trancriptional regulatory protein; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
  
   
 0.787
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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