STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY4635Conserved hypothetical protein; Possible endonuclease which induces a single-strand cut and initiates DNA replication. (804 aa)    
Predicted Functional Partners:
STY4638
Similar to Bacteriophage P2 hypothetical 8.2 kDa protein in gpa 5'region orf82 SW:YO82_BPP2 (Q06424) (74 aa) fasta scores: E(): 5.3e-10, 47.1% id in 70 aa and bacteriophage 186 hypothetical 8.5 kDa protein CP80 SW:CP80_BP186 (P41059) (75 aa) fasta scores: E(): 1.6e-19, 69.3% id in 75 aa. Also similar to Escherichia coli TraR zinc finger protein SW:TRAR_ECOLI (P41065) (73 aa) fasta scores: E(): 1.1e-05, 38.9% id in 72 aa. Four cysteines postulated to be required for zinc binding in TraR are conserved.
 
    0.986
STY4645
Similar to Bacteriophage S2 Integrase TR:P79671 (EMBL:Z71579) (337 aa) fasta scores: E(): 0, 54.1% id in 340 aa and Bacteriophage 186 integrase SW:VINT_BP186 (P06723) (336 aa) fasta scores: E(): 0, 55.5% id in 344 aa.
 
    0.982
STY4623
Similar to Bacteriophage P2 head completion/stabilization protein L SW:VPL_BPP2 (P25475) (169 aa) fasta scores: E(): 4.7e-22, 40.4% id in 151 aa.
  
    0.981
STY4605
Putative phage tail protein; Similar to Bacteriophage P2 complete genome E, essential tail protein TR:O64313 (EMBL:AF063097) (91 aa) fasta scores: E(): 3.3e-12, 44.8% id in 87 aa.
  
    0.973
STY4615
Similar to Bacteriophage P2 baseplate assembly protein V SW:VPV_BPP2 (P31340) (211 aa) fasta scores: E(): 2.4e-22, 41.9% id in 210 aa Bacteriophage 186 Orf32 TR:O80314 (EMBL:U32222) (213 aa) fasta scores: E(): 1.2e-23, 45.3% id in 201 aa.
  
    0.970
STY3674
Similar to Bacteriophage 186 capsid portal protein W TR:Q37851 (EMBL:U32222) (340 aa) fasta scores: E(): 0, 62.0% id in 342 aa and to Bacteriophage P2 presumed portal vertex protein Q SW:VPQ_BPP2 (P25480) (344 aa) fasta scores: E(): 0, 61.7% id in 342 aa.
  
    0.964
STY4626
Putative capsid protein; Similar to Bacteriophage P2 presumed capsid scaffolding protein O SW:VPO_BPP2 (P25478) (284 aa) fasta scores: E(): 0, 45.0% id in 280 aa.
  
    0.956
STY4627
Probable terminase subunit; Similar to Bacteriophage P2 terminase, ATPase subunit P SW:VPP_BPP2 (P25479) (590 aa) fasta scores: E(): 0, 63.1% id in 590 aa and to Bacteriophage 186 terminase subunit TR:Q9T0R3 (EMBL:U32222) (589 aa) fasta scores: E(): 0, 63.0% id in 579 aa.
  
  
 0.956
STY3675
Similar to Bacteriophage P2 terminase, ATPase subunit P SW:VPP_BPP2 (P25479) (590 aa) fasta scores: E(): 0, 63.9% id in 590 aa and to Bacteriophage 186 terminase subunit TR:Q9T0R3 (EMBL:U32222) (589 aa) fasta scores: E(): 0, 63.4% id in 579 aa.
  
  
 0.955
STY3676
Similar to Bacteriophage P2 presumed capsid scaffolding protein O SW:VPO_BPP2 (P25478) (284 aa) fasta scores: E(): 0, 48.0% id in 281 aa, and to Bacteriophage 186 v protein V TR:Q01088 (EMBL:U32222) (284 aa) fasta scores: E(): 0, 46.3% id in 281 aa.
  
    0.951
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.