STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (322 aa)    
Predicted Functional Partners:
STY3153
2-acylglycerophosphoethanolamine acyl transferase/acyl carrier protein synthetase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
    
 0.933
STY2845
CDP-diacylglycerol-serine O-phosphatidyltransferase; Orthologue of E. coli pssA (PSS_ECOLI); Fasta hit to PSS_ECOLI (451 aa), 94% identity in 451 aa overlap.
  
 0.930
STY3602
Detergent-resistant phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities; Belongs to the phospholipase A1 family.
  
  
  0.915
yjeP
Putative membrane protein; Similar to Escherichia coli hypothetical 123.8 kDa protein in genx-psd intergenic region precursor yjeP SW:YJEP_ECOLI (P39285) (1107 aa) fasta scores: E(): 0, 89.0% id in 1108 aa.Contains possible membrane spanning hydrophobic domains.
     
 0.819
STY2153
Phosphotidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 
 0.776
STY0187
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
  
   
 0.692
orn
Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
 
     0.605
yjeQ
Putative membrane protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
    0.586
STY1185
Conserved hypothetical protein; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily.
   
 0.576
STY3110
L-serine dehydratase 2 (L-serine deaminase 2); Fasta hit to TDCG_ECOLI (454 aa), 73% identity in 454 aa overlap; Fasta hit to SDHL_ECOLI (454 aa), 77% identity in 455 aa overlap; Orthologue of E. coli sdaB (SDHM_ECOLI); Fasta hit to SDHM_ECOLI (455 aa), 94% identity in 455 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family.
      
 0.537
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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