STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY4874Putative sugar transport protein; Similar to Escherichia coli hypothetical protein YjiO yjiO SW:YJIO_ECOLI (P39386) (410 aa) fasta scores: E(): 0, 86.0% id in 408 aa and to Escherichia coli multidrug translocase mdfA SW:MDFA_ECOLI (Q46966) (410 aa) fasta scores: E(): 0, 40.2% id in 386 aa. (413 aa)    
Predicted Functional Partners:
STY0901
Putative membrane protein; Similar to Escherichia coli MosC protein mosC TR:P75810 (EMBL:AE000186) (402 aa) fasta scores: E(): 0, 88.1% id in 402 aa, and to Rhizobium meliloti membrane protein MosC mosC SW:MOSC_RHIME (Q07609) (407 aa) fasta scores: E(): 5.3e-07, 25.8% id in 395 aa; Orthologue of E. coli P75810; Fasta hit to P75810 (402 aa), 88% identity in 402 aa overlap.
   
  
 0.864
STY1191
Putative membrane transport protein; Similar to Streptococcus pneumoniae multi-drug resistance efflux pump PmraATR:Q9ZEX9 (EMBL:AJ007367) (399 aa) fasta scores: E(): 0, 44.4% id in 390 aa; Orthologue of E. coli yceE (YCEE_ECOLI); Fasta hit to YCEE_ECOLI (408 aa), 90% identity in 403 aa overlap.
  
  
 0.813
STY1452
Conserved hypothetical protein; Fasta hit to P77585 (345 aa), 32% identity in 349 aa overlap; Orthologue of E. coli yjhO (SGCX_ECOLI); Fasta hit to SGCX_ECOLI (383 aa), 84% identity in 372 aa overlap.
      
 0.803
STY1204
Putative membrane transporter; Orthologue of E. coli YCEL_ECOLI; Fasta hit to YCEL_ECOLI (402 aa), 91% identity in 402 aa overlap.
      
 0.643
ybjZ
Conserved hypothetical ABC transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.585
STY0519
Acriflavin resistance protein B; Fasta hit to ACRF_ECOLI (1034 aa), 78% identity in 1033 aa overlap; Fasta hit to YHIV_ECOLI (1037 aa), 71% identity in 1035 aa overlap; Fasta hit to ACRD_ECOLI (1037 aa), 65% identity in 1036 aa overlap; Orthologue of E. coli acrB (ACRB_ECOLI); Fasta hit to ACRB_ECOLI (1049 aa), 95% identity in 1048 aa overlap.
    
 
 0.570
STY4873
Putative membrane protein; Similar to Escherichia coli hypothetical protein YjiN yjiN SW:YJIN_ECOLI (P39385) (426 aa) fasta scores: E(): 0, 89.8% id in 423 aa. Also similar to Mycobacterium tuberculosis putative membrane protein Rv0473 or MTV038.17 TR:O53758 (EMBL:AL021933) (456 aa) fasta scores: E(): 5.2e-17, 31.4% id in 423 aa.
       0.547
bcr
Similar to Escherichia coli bicyclomycin resistance protein bcr or bicA or bicR or sur or suxA SW:BCR_ECOLI (P28246) (396 aa) fasta scores: E(): 0, 93.2% id in 396 aa. Contains hydrophobic, probable membrane-spannign regions.
  
   
0.521
STY0908
Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family.
   
    0.510
STY2489
Putative ABC transporter ATP-binding protein; Orthologue of E. coli yojI (YOJI_ECOLI); Fasta hit to YOJI_ECOLI (547 aa), 91% identity in 547 aa overlap. Contains hydrophobic, probable membrane-spanning regions.
      
 0.506
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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