STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smpPutative membrane protein; Similar to Escherichia coli smp protein precursor SW:SMP_ECOLI (P18838) (214 aa) fasta scores: E(): 0, 91.1% id in 214 aa. (214 aa)    
Predicted Functional Partners:
STY2136
Conserved hypothetical protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
   
 0.814
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.771
STY3777
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.768
STY0789
Putative membrane protein; Similar to Escherichia coli 10.9 kDa protein in cydb-tolq intergenic region SW:YBGE_ECOLI (P37343) (97 aa) fasta scores: E(): 0, 86.7% id in 90 aa, and to Vibrio cholerae hypothetical protein Vc1841 vc1841 TR:Q9KR06 (EMBL:AE004260) (105 aa) fasta scores: E(): 1.2e-09, 38.5% id in 78 aa.
  
     0.767
STY1097
Helicase IV (75 kD helicase); Orthologue of E. coli helD (HELD_ECOLI); Fasta hit to HELD_ECOLI (684 aa), 84% identity in 684 aa overlap.
  
     0.766
STY3543
Conserved hypothetical protein; Fasta hit to YCFR_ECOLI (85 aa), 34% identity in 89 aa overlap; Fasta hit to YJFN_ECOLI (100 aa), 34% identity in 93 aa overlap; Fasta hit to YJFY_ECOLI (91 aa), 30% identity in 86 aa overlap; Fasta hit to YKGI_ECOLI (83 aa), 35% identity in 80 aa overlap; Fasta hit to YBIJ_ECOLI (86 aa), 37% identity in 90 aa overlap; Paralogue of E. coli YHCN_ECOLI; Fasta hit to YHCN_ECOLI (87 aa), 53% identity in 88 aa overlap.
  
     0.766
STY1254
Putative secreted protein; Fasta hit to YHCN_ECOLI (87 aa), 38% identity in 88 aa overlap; Paralogue of E. coli ybiJ (YBIJ_ECOLI); Fasta hit to YBIJ_ECOLI (86 aa), 48% identity in 86 aa overlap.
  
     0.765
STY0860
Putative exported protein; Fasta hit to YHCN_ECOLI (87 aa), 48% identity in 88 aa overlap; Fasta hit to YCFR_ECOLI (85 aa), 45% identity in 86 aa overlap; Fasta hit to YAHO_ECOLI (91 aa), 32% identity in 91 aa overlap; Orthologue of E. coli ybiJ (YBIJ_ECOLI); Fasta hit to YBIJ_ECOLI (86 aa), 80% identity in 86 aa overlap. Contains probable N-terminal signal sequence.
  
     0.764
STY0262
ROF protein; Orthologue of E. coli yaeO (ROF_ECOLI); Fasta hit to ROF_ECOLI (84 aa), 81% identity in 84 aa overlap.
  
     0.758
STY4045
Putative exported protein; Similar to Escherichia coli hypothetical 62.3 kDa protein in glts-selc intergenic region yicH SW:YICH_ECOLI (P31433) (569 aa) fasta scores: E(): 0, 79.9% id in 567 aa.
  
     0.753
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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