STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltDSimilar to Escherichia coli membrane-bound lytic murein transglycosylase d precursor mltd or dniR SW:MLTD_ECOLI (P23931; P32982; P77350) (452 aa) fasta scores: E(): 0, 91.4% id in 455 aa, and to Neisseria meningitidis |+++ unknown: ox in cab84739 +++| putative membrane bound murein transglycosylase TR:CAB84739 (EMBL:AL162756) (658 aa) fasta scores: E(): 4.4e-32, 35.2% id in 341 aa, and to Bacteriophage phi-LC3 LysB lysB TR:Q37969 (EMBL:U04309) (429 aa) fasta scores: E(): 3.9e-06, 30.4% id in 161 aa; Orthologue of E. coli dniR (MLTD_ECOLI); Fasta hit to MLTD_ECOLI (452 aa), 91% identity [...] (455 aa)    
Predicted Functional Partners:
STY1218
Flagellar basal-body rod protein FlgG (distal rod protein); Fasta hit to FLGF_ECOLI (251 aa), 32% identity in 261 aa overlap; Orthologue of E. coli flgG (FLGG_ECOLI); Fasta hit to FLGG_ECOLI (260 aa), 99% identity in 260 aa overlap; Belongs to the flagella basal body rod proteins family.
  
 
 0.701
gloB
Probable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
       0.657
STY2828
Signal peptidase I; Identical to Salmonella typhimurium signal peptidase I lepB SW:LEP_SALTY (P23697) (324 aa) fasta scores: E(): 0, 100.0% id in 324 aa; Orthologue of E. coli lepB (LEP_ECOLI); Fasta hit to LEP_ECOLI (324 aa), 94% identity in 324 aa overlap; Belongs to the peptidase S26 family.
 
  
 0.643
STY0958
Cell division protein FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA [...]
  
  
 0.641
STY0179
Probable secreted protein; No database matches. Contains N-terminal signal sequence.
  
 
 0.576
STY2751
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.557
STY0689
Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family.
  
  
 0.552
STY0305
Putative membrane protein; Similar in C-terminus to various proteins including Vibrio parahaemolyticus sodium-driven polar flagellar protein motB TR:Q9Z6G9 (EMBL:AF069391) (315 aa) fasta scores: E(): 4e-08, 33.1% id in 139 aa, and to Bordetella avium outer membrane protein a precursor ompA SW:OMPA_BORAV (Q05146) (194 aa) fasta scores: E(): 1.8e-07, 36.2% id in 116 aa.
  
  
 0.551
STY3507
Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.
 
   
 0.549
STY2098
Conserved hypothetical protein; Unknown function. Similar to many bacterial hypothetical proteins; Orthologue of E. coli yebA (YEBA_ECOLI); Fasta hit to YEBA_ECOLI (419 aa), 92% identity in 419 aa overlap.
 
  
 0.544
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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