STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybaVPutative exported protein; Similar to Escherichia coli hypothetical 12.7 kDa protein in hupb-cof intergenic region ybaV SW:YBAV_ECOLI (P77415) (123 aa) fasta scores: E(): 0, 83.9% id in 124 aa, and to C-terminus of Streptococcus pneumoniae competence protein celA TR:O85197 (EMBL:AF052208) (216 aa) fasta scores: E(): 8.8e-05, 35.9% id in 92 aa, and Bacillus subtilis come operon protein 1 comea or come1 SW:CME1_BACSU (P39694) (205 aa) fasta scores: E(): 0.00047, 39.4% id in 71 aa. Contains probable N-terminal signal sequence; Orthologue of E. coli YBAV_ECOLI; Fasta hit to YBAV_ECOLI (123 [...] (124 aa)    
Predicted Functional Partners:
STY0984
Putative competence-related protein; Similar to Escherichia coli hypothetical protein YcaI SW:YCAI_ECOLI (P37443) (780 aa) fasta scores: E(): 0, 69.9% id in 754 aa, and to Pseudomonas stutzeri competence protein ComA TR:Q9XAU3 (EMBL:AJ243354) (741 aa) fasta scores: E(): 0, 31.1% id in 765 aa, and to Haemophilus influenzae recombination protein 2 rec2 or rec-2 or hi0061 SW:REC2_HAEIN (P44408) (788 aa) fasta scores: E(): 0, 30.6% id in 808 aa, and to Neisseria gonorrhoeae competence protein ComA comA SW:COMA_NEIGO (P51973) (691 aa) fasta scores: E(): 7.2e-24, 27.7% id in 703 aa; Ortholog [...]
 
  
 0.794
STY0496
Conserved hypothetical protein; Fasta hit to YBGC_ECOLI (134 aa), 34% identity in 117 aa overlap; Orthologue of E. coli YBAW_ECOLI; Fasta hit to YBAW_ECOLI (132 aa), 95% identity in 132 aa overlap.
 
     0.591
STY3107
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
     
 0.584
STY3138
Prepilin peptidase dependent protein A precursor; Orthologue of E. coli ppdA (PPDA_ECOLI); Fasta hit to PPDA_ECOLI (156 aa), 67% identity in 155 aa overlap.
 
  
 0.577
STY0164
Similar to Escherichia coli protein transport protein hofC or HopC SW:HOFC_ECOLI (P36646; P75648) fasta scores: E(): 0, 68.0% id in 400 aa, and to Vibrio cholerae type IV-A pilus assembly protein pilC TR:Q9X4G9 (EMBL:AF109904) fasta scores: E(): 0, 31.4% id in 401 aa. Also similar to Pseudomonas aeruginosa fimbrial assembly protein pilC SW:PILC_PSEAE (P22609) fasta scores: E(): 0, 26.7% id in 393 aa; Orthologue of E. coli hofC (HOFC_ECOLI); Fasta hit to HOFC_ECOLI (400 aa), 68% identity in 400 aa overlap.
  
  
 0.560
pilR
Putative membrane protein; Previously sequenced Salmonella typhi PilR TR:Q9ZIV0 (EMBL:AF000001) (361 aa) fasta scores: E(): 0, 100.0% id in 361 aa. Also similar to Escherichia coli plasmid IncI1 R64 integral membrane protein pilR TR:O07376 (EMBL:D88588) (365 aa) fasta scores: E(): 0, 44.5% id in 357 aa. Contains possible membrane spanning hydrophobic domains.
  
  
 0.560
hopD
Similar to Salmonella typhimurium leader peptidase HopD hopD SW:HOPD_SALTY (O68927) (155 aa) fasta scores: E(): 0, 99.4% id in 155 aa, and to Escherichia coli leader peptidase HopD hopD SW:HOPD_ECOLI (O68932) (155 aa) fasta scores: E(): 0, 68.9% id in 148 aa; Belongs to the peptidase A24 family.
   
  
 0.528
pilU
Prepilin peptidase; Previously sequenced Salmonella typhi PilU protein TR:Q9ZIU7 (EMBL:AF000001) (220 aa) fasta scores: E(): 0, 100.0% id in 220 aa. Also similar to Escherichia coli plasmid IncI1 R64 prepilin peptidase pilU TR:O07379 (EMBL:D88588) (218 aa) fasta scores: E(): 2e-25, 34.4% id in 221 aa. Contains multiple possible membrane spanning hydrophobic domains.
   
  
 0.528
ppiD
Similar to Escherichia coli peptidyl-prolyl cis-trans isomerase d ppiD SW:CYPD_ECOLI (P77241) (623 aa) fasta scores: E(): 0, 88.5% id in 624 aa; Orthologue of E. coli CYPD_ECOLI; Fasta hit to CYPD_ECOLI (623 aa), 89% identity in 624 aa overlap.
       0.519
STY0165
Similar to Escherichia coli protein transport protein HofB of HopB SW:HOFB_ECOLI (P36645; P75649; Q47022) fasta scores: E(): 0, 69.7% id in 459 aa, and to Pseudomonas aeruginosa fimbrial assembly protein PilB SW:PILB_PSEAE (P22608) fasta scores: E(): 0, 38.4% id in 485 aa, and to Vibrio cholerae general secretion pathway protein e EPSE SW:GSPE_VIBCH (P37093) fasta scores: E(): 0, 46.0% id in 378 aa; Fasta hit to GSPE_ECOLI (493 aa), 44% identity in 400 aa overlap; Orthologue of E. coli hofB (HOFB_ECOLI); Fasta hit to HOFB_ECOLI (461 aa), 70% identity in 459 aa overlap.
  
  
 0.517
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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