STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcuCSimilar to Escherichia coli C4-dicarboxylate anaerobic carrier dcuC SW:DCUC_ECOLI (Q47134) (461 aa) fasta scores: E(): 0, 93.0% id in 460 aa; Fasta hit to YHCL_ECOLI (455 aa), 36% identity in 447 aa overlap; Orthologue of E. coli DCUC_ECOLI; Fasta hit to DCUC_ECOLI (461 aa), 93% identity in 460 aa overlap. (461 aa)    
Predicted Functional Partners:
STY4899
Putative membrane protein; Similar to Escherichia coli hypothetical protein YjjP yjjP SW:YJJP_ECOLI (P39402) (277 aa) fasta scores: E(): 0, 89.0% id in 264 aa.
  
     0.722
STY1286
Nitrate/nitrite sensor protein NarX; Fasta hit to NARQ_ECOLI (566 aa), 30% identity in 598 aa overlap; Orthologue of E. coli narX (NARX_ECOLI); Fasta hit to NARX_ECOLI (598 aa), 86% identity in 598 aa overlap.
  
   
 0.697
STY4898
Putative membrane protein; Similar to Escherichia coli 14.1 kDa protein in dnat-bglj intergenic region SW:YJJB_ECOLI () (128 aa) fasta scores: E(): 0, 89.4% id in 104 aa. Contains transmembrane regions.
  
     0.679
STY3206
Similar to Escherichia coli hypothetical protein YqfB SW:YQFB_ECOLI (Q46828) (103 aa) fasta scores: E(): 0, 87.4% id in 103 aa; Belongs to the UPF0267 family.
  
     0.665
frdA
Similar to Escherichia coli fumarate reductase flavoprotein subunit SW:FRDA_ECOLI (P00363) (601 aa) fasta scores: E(): 0, 95.3% id in 594 aa, and to Proteus vulgaris fumarate reductase flavoprotein subunit frdA SW:FRDA_PROVU (P20922) (598 aa) fasta scores: E(): 0, 85.5% id in 598 aa.
  
   
 0.660
STY1175
Putative membrane protein; Fasta hit to YAHC_ECOLI (165 aa), 30% identity in 156 aa overlap; Orthologue of E. coli YCDZ_ECOLI; Fasta hit to YCDZ_ECOLI (179 aa), 84% identity in 179 aa overlap.
  
     0.650
STY2266
Putative DNA gyrase inhibitory protein; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
  
     0.616
frdC
Fumarate reductase complex subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
    0.580
dcuA
Anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
  
   
 0.579
STY0485
Cytochrome o ubiquinol oxidase subunit II; Orthologue of E. coli cyoA (CYOA_ECOLI); Fasta hit to CYOA_ECOLI (315 aa), 96% identity in 315 aa overlap.
      
 0.576
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.