STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xisExcisionase; Similar to Escherichia coli O157:H7 excisionase Xis TR:BAA94100 (EMBL:AP000422) fasta scores: E(): 5.4e-14, 49.4% id in 77 aa. (82 aa)    
Predicted Functional Partners:
STY1412
Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
      
 0.812
STY2073
Exodeoxyribonuclease VIII; N-terminal approx. 750 aa is similar to the corresponding region of Escherichia coli exodeoxyribonuclease VIII recE SW:RECE_ECOLI (P15032; P77807; P76848) (866 aa) fasta scores: E(): 0, 67.1% id in 750 aa, while the remainder is similar to Salmonella typhimurium exodeoxyribonuclease VIII recE TR:O30354 (EMBL:AF001386) (975 aa) fasta scores: E(): 0, 37.7% id in 1056 aa.
      
 0.810
int
Integrase; Similar to Bacteriophage 933W, and Bacteriophage VT2-Sa integrase int TR:Q9XJG6 (EMBL:AF125520) fasta scores: E(): 0, 60.4% id in 427 aa, and to Escherichia coli O157:H7 integrase INT TR:BAA94099 (EMBL:AP000422) fasta scores: E(): 0, 60.4% id in 427 aa; Belongs to the 'phage' integrase family.
       0.783
STY1416
Conserved hypothetical protein; Fasta hit to UP12_ECOLI (142 aa), 40% identity in 146 aa overlap; Orthologue of E. coli UP03_ECOLI; Fasta hit to UP03_ECOLI (144 aa), 91% identity in 144 aa overlap.
      
 0.687
STY1013
Putative bacteriophage protein; No significant database matches.
  
    0.646
STY1014
Putative DNA methylase; Paralogue of E. coli dam (DMA_ECOLI); Fasta hit to DMA_ECOLI (278 aa), 46% identity in 266 aa overlap.
       0.645
STY1015
Putative bacteriophage protein; No significant database matches.
       0.645
STY4627
Probable terminase subunit; Similar to Bacteriophage P2 terminase, ATPase subunit P SW:VPP_BPP2 (P25479) (590 aa) fasta scores: E(): 0, 63.1% id in 590 aa and to Bacteriophage 186 terminase subunit TR:Q9T0R3 (EMBL:U32222) (589 aa) fasta scores: E(): 0, 63.0% id in 579 aa.
      
 0.563
STY4906
Conserved hypothetical protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
      
 0.505
STY1016
Exonuclease; Similar to Bacteriophage lambda exonuclease Exo or RedX or RED-ALPHA SW:EXO_LAMBD (P03697) fasta scores: E(): 0, 84.5% id in 226 aa.
       0.476
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.